Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 2 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 3 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 4 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 5 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 6 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 7 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 8 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 9 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
EGFR [3] EGFR, ERBB2, FLT4 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 10 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 11 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 12 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 13 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 14 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 15 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 16 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 17 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 18 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [3] EGFR, ERBB2, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 19 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 20 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 21 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 22 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 23 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 24 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 25 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 26 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 27 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 28 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 29 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 30 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 31 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 32 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 33 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 34 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 35 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 36 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 37 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 38 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 39 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 40 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 41 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 42 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 43 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 44 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 45 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 46 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 47 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 48 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 49 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 50 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 51 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EGFR [3] EGFR, ERBB2, FLT4 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 52 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 53 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 54 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 55 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
ERBB2 [1] ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 56 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
ERBB2 [1] ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 57 | Platinum drug resistance 💬 9 genes, 15 drugs (DrugBank) and 23 diseases |
ERBB2 [1] ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 58 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 59 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 60 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 61 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [2] EGFR, ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 62 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 63 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [3] EGFR, ERBB2, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
| 64 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
ERBB2 [1] ERBB2 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 [3] 34, 74, 75 💬
|
| 65 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
ERBB2 [1] ERBB2 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 [1] 34 💬
|
| 66 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
ERBB2 [1] ERBB2 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|