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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Calcium signaling pathway 💬

[3] FGFR1, FGFR2, FGFR3 💬

Infigratinib 💬

Infigratinib

[1] 276 💬

Calcium signaling pathway 💬

[8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬

Name	Full Name
FGFR1	fibroblast growth factor receptor 1
FGFR2	fibroblast growth factor receptor 2
FGFR3	fibroblast growth factor receptor 3
FLT1	fms related receptor tyrosine kinase 1
FLT4	fms related receptor tyrosine kinase 4
KDR	kinase insert domain receptor
PDGFRA	platelet derived growth factor receptor alpha
PDGFRB	platelet derived growth factor receptor beta

Nintedanib 💬

Nintedanib

[5] 51, 85, 89, 227, 228 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
89	Lymphangioleiomyomatosis;LAM;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Calcium signaling pathway 💬

[1] FGFR2 💬

Palifermin 💬

Palifermin

[5] 13, 36, 38, 39, 65 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
36	Epidermolysis bullosa;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
65	Primary immunodeficiency;

Central carbon metabolism in cancer 💬

[3] FGFR1, FGFR2, FGFR3 💬

Infigratinib 💬

Infigratinib

[1] 276 💬

Central carbon metabolism in cancer 💬

[5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬

Name	Full Name
FGFR1	fibroblast growth factor receptor 1
FGFR2	fibroblast growth factor receptor 2
FGFR3	fibroblast growth factor receptor 3
PDGFRA	platelet derived growth factor receptor alpha
PDGFRB	platelet derived growth factor receptor beta

Nintedanib 💬

Nintedanib

[5] 51, 85, 89, 227, 228 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
89	Lymphangioleiomyomatosis;LAM;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Central carbon metabolism in cancer 💬

[1] FGFR2 💬

Palifermin 💬

Palifermin

[5] 13, 36, 38, 39, 65 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
36	Epidermolysis bullosa;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
65	Primary immunodeficiency;

EGFR tyrosine kinase inhibitor resistance 💬

[1] FGFR2 💬

Palifermin 💬

Palifermin

[5] 13, 36, 38, 39, 65 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
36	Epidermolysis bullosa;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
65	Primary immunodeficiency;

EGFR tyrosine kinase inhibitor resistance 💬

[2] FGFR2, FGFR3 💬

Infigratinib 💬

Infigratinib

[1] 276 💬

EGFR tyrosine kinase inhibitor resistance 💬

[5] FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬

Name	Full Name
FGFR2	fibroblast growth factor receptor 2
FGFR3	fibroblast growth factor receptor 3
KDR	kinase insert domain receptor
PDGFRA	platelet derived growth factor receptor alpha
PDGFRB	platelet derived growth factor receptor beta

Nintedanib 💬

Nintedanib

[5] 51, 85, 89, 227, 228 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
89	Lymphangioleiomyomatosis;LAM;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

Endocytosis 💬

[1] FGFR2 💬

Palifermin 💬

Palifermin

[5] 13, 36, 38, 39, 65 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
36	Epidermolysis bullosa;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
65	Primary immunodeficiency;

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