Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Bladder cancer 💬
[1] FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
2 Bladder cancer 💬
[1] FGFR3 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
3 Calcium signaling pathway 💬
[3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
4 Calcium signaling pathway 💬
[8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
5 Central carbon metabolism in cancer 💬
[3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
6 Central carbon metabolism in cancer 💬
[5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
7 EGFR tyrosine kinase inhibitor resistance 💬
[2] FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
8 EGFR tyrosine kinase inhibitor resistance 💬
[5] FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
9 Endocytosis 💬
[2] FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
10 Endocytosis 💬
[3] FGFR2, FGFR3, PDGFRA 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
11 MAPK signaling pathway 💬
[3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
12 MAPK signaling pathway 💬
[8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
13 MicroRNAs in cancer 💬
[1] FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
14 MicroRNAs in cancer 💬
[3] FGFR3, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
15 Pathways in cancer 💬
[3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
16 Pathways in cancer 💬
[6] FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
17 PI3K-Akt signaling pathway 💬
[3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
18 PI3K-Akt signaling pathway 💬
[8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
19 Rap1 signaling pathway 💬
[3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
20 Rap1 signaling pathway 💬
[8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
21 Ras signaling pathway 💬
[3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
22 Ras signaling pathway 💬
[8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
23 Regulation of actin cytoskeleton 💬
[3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
24 Regulation of actin cytoskeleton 💬
[5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
25 Signaling pathways regulating pluripotency of stem cells 💬
[3] FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib [1] 276 💬
26 Signaling pathways regulating pluripotency of stem cells 💬
[3] FGFR1, FGFR2, FGFR3 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬