Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
[4] BRAF, FLT3, KIT, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
2 Acute myeloid leukemia 💬
[3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
3 Acute myeloid leukemia 💬
[3] CSF1R, FLT3, KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
4 Central carbon metabolism in cancer 💬
[2] FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
5 Central carbon metabolism in cancer 💬
[5] FLT3, KIT, PDGFRA, PDGFRB, RET 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
6 Central carbon metabolism in cancer 💬
[5] FLT3, KIT, PDGFRB, RAF1, RET 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
7 Hematopoietic cell lineage 💬
[3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
8 Hematopoietic cell lineage 💬
[3] CSF1R, FLT3, KIT 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
9 Hematopoietic cell lineage 💬
[2] FLT3, KIT 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
10 MAPK signaling pathway 💬
[7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
11 MAPK signaling pathway 💬
[8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
12 MAPK signaling pathway 💬
[3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
13 Pathways in cancer 💬
[7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
14 Pathways in cancer 💬
[7] CSF1R, FLT3, FLT4, KIT, PDGFRA, PDGFRB, RET 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
15 Pathways in cancer 💬
[3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
16 PI3K-Akt signaling pathway 💬
[8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
17 PI3K-Akt signaling pathway 💬
[3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
18 PI3K-Akt signaling pathway 💬
[6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
19 Ras signaling pathway 💬
[8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
20 Ras signaling pathway 💬
[3] CSF1R, FLT3, KIT 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
21 Ras signaling pathway 💬
[6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
22 Transcriptional misregulation in cancer 💬
[3] CSF1R, FLT1, FLT3 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
23 Transcriptional misregulation in cancer 💬
[2] CSF1R, FLT3 💬 Pexidartinib 💬 Pexidartinib [1] 34 💬
24 Transcriptional misregulation in cancer 💬
[1] FLT3 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬