Target Gene/Pathway Pathway / Gene

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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Calcium signaling pathway 💬

[8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬

Name	Full Name
ADRA1A	adrenoceptor alpha 1A
ADRA1B	adrenoceptor alpha 1B
ADRA1D	adrenoceptor alpha 1D
HRH1	histamine receptor H1
HTR2A	5-hydroxytryptamine receptor 2A
HTR2B	5-hydroxytryptamine receptor 2B
HTR2C	5-hydroxytryptamine receptor 2C
HTR6	5-hydroxytryptamine receptor 6

Olanzapine 💬

[2] 2 , 8 💬

2

Calcium signaling pathway 💬

[8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬

Name	Full Name
CHRM1	cholinergic receptor muscarinic 1
CHRM2	cholinergic receptor muscarinic 2
CHRM3	cholinergic receptor muscarinic 3
CHRM5	cholinergic receptor muscarinic 5
HRH1	histamine receptor H1
HTR2A	5-hydroxytryptamine receptor 2A
HTR2B	5-hydroxytryptamine receptor 2B
HTR2C	5-hydroxytryptamine receptor 2C

Chlorpromazine 💬

[1] 254 💬

3

Calcium signaling pathway 💬

[1] HTR2A 💬

Aripiprazole 💬

[2] 6 , 206 💬

4

Calcium signaling pathway 💬

[1] HTR2A 💬

Cariprazine 💬

[1] 21 💬

5

Calcium signaling pathway 💬

[1] HTR2A 💬

Nelotanserin 💬

[1] 6 💬

6

Calcium signaling pathway 💬

[1] HTR2A 💬

Quetiapine 💬

[2] 6 , 13 💬

7

Calcium signaling pathway 💬

[1] HTR2A 💬

Risperidone 💬

[5] 8 , 156, 179, 187, 206 💬

8

Calcium signaling pathway 💬

[3] HTR2A, HTR2B, HTR2C 💬

Iloperidone 💬

[1] 6 💬

9

Calcium signaling pathway 💬

[3] HTR2A, HTR2B, HTR2C 💬

[1] 2 💬

10

Calcium signaling pathway 💬

[2] HTR2A, HTR2C 💬

[1] 6 💬

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