Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
2 Calcium signaling pathway 💬
 [8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
3 Calcium signaling pathway 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
4 Calcium signaling pathway 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
5 Calcium signaling pathway 💬
 [2] HTR2A, HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
6 Calcium signaling pathway 💬
 [2] HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
7 Calcium signaling pathway 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
8 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
9 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
10 Gap junction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
11 Gap junction 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
12 Gap junction 💬
 [2] HTR2A, HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
13 Gap junction 💬
 [2] HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
14 Gap junction 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
15 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
16 Inflammatory mediator regulation of TRP channels 💬
 [4] HRH1, HTR2A, HTR2B, HTR2C 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
17 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
18 Inflammatory mediator regulation of TRP channels 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
19 Inflammatory mediator regulation of TRP channels 💬
 [2] HTR2A, HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
20 Inflammatory mediator regulation of TRP channels 💬
 [2] HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
21 Inflammatory mediator regulation of TRP channels 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬
22 Neuroactive ligand-receptor interaction 💬
 [11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
23 Neuroactive ligand-receptor interaction 💬
 [13] ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
24 Neuroactive ligand-receptor interaction 💬
 [6] ADRA2A, ADRA2B, ADRA2C, DRD4, HTR2A, HTR2C 💬 Clozapine 💬 Clozapine [1]  6  💬
25 Neuroactive ligand-receptor interaction 💬
 [4] DRD2, HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
26 Neuroactive ligand-receptor interaction 💬
 [3] HTR1D, HTR2A, HTR2C 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
27 Neuroactive ligand-receptor interaction 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Trazodone 💬 Trazodone [1]  2  💬
28 Neuroactive ligand-receptor interaction 💬
 [3] HTR2C, MTNR1A, MTNR1B 💬 Agomelatine 💬 Agomelatine [1]  6  💬
29 Serotonergic synapse 💬
 [4] HTR1D, HTR2A, HTR2C, SLC6A4 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
30 Serotonergic synapse 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine [1] 254 💬
31 Serotonergic synapse 💬
 [3] HTR2A, HTR2B, HTR2C 💬 Iloperidone 💬 Iloperidone [1]  6  💬
32 Serotonergic synapse 💬
 [4] HTR2A, HTR2B, HTR2C, HTR6 💬 Olanzapine 💬 Olanzapine [2]  2 ,  8  💬
33 Serotonergic synapse 💬
 [4] HTR2A, HTR2B, HTR2C, SLC6A4 💬 Trazodone 💬 Trazodone [1]  2  💬
34 Serotonergic synapse 💬
 [7] HTR2A, HTR2C, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬 Clozapine 💬 Clozapine [1]  6  💬
35 Serotonergic synapse 💬
 [1] HTR2C 💬 Agomelatine 💬 Agomelatine [1]  6  💬

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