Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Coronavirus disease - COVID-19 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
2 Coronavirus disease - COVID-19 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
3 Coronavirus disease - COVID-19 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
4 Coronavirus disease - COVID-19 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
5 Coronavirus disease - COVID-19 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
6 Coronavirus disease - COVID-19 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
7 Coronavirus disease - COVID-19 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
8 Cytokine-cytokine receptor interaction 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
9 Cytokine-cytokine receptor interaction 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
10 Cytokine-cytokine receptor interaction 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
11 Cytokine-cytokine receptor interaction 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
12 Cytokine-cytokine receptor interaction 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
13 Cytokine-cytokine receptor interaction 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
14 Cytokine-cytokine receptor interaction 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
15 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
16 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
17 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
18 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
19 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
20 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
21 Epstein-Barr virus infection 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
22 Hepatitis C 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
23 Hepatitis C 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
24 Hepatitis C 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
25 Hepatitis C 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
26 Hepatitis C 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
27 Hepatitis C 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
28 Hepatitis C 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
29 Herpes simplex virus 1 infection 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
30 Herpes simplex virus 1 infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
31 Herpes simplex virus 1 infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
32 Herpes simplex virus 1 infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
33 Herpes simplex virus 1 infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
34 Herpes simplex virus 1 infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
35 Herpes simplex virus 1 infection 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
36 Human papillomavirus infection 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
37 Human papillomavirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
38 Human papillomavirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
39 Human papillomavirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
40 Human papillomavirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
41 Human papillomavirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
42 Human papillomavirus infection 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
43 Influenza A 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
44 Influenza A 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
45 Influenza A 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
46 Influenza A 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
47 Influenza A 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
48 Influenza A 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
49 Influenza A 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
50 JAK-STAT signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
51 JAK-STAT signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
52 JAK-STAT signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
53 JAK-STAT signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
54 JAK-STAT signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
55 JAK-STAT signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
56 JAK-STAT signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
57 Kaposi sarcoma-associated herpesvirus infection 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
58 Kaposi sarcoma-associated herpesvirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
59 Kaposi sarcoma-associated herpesvirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
60 Kaposi sarcoma-associated herpesvirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
61 Kaposi sarcoma-associated herpesvirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
62 Kaposi sarcoma-associated herpesvirus infection 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
63 Kaposi sarcoma-associated herpesvirus infection 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
64 Measles 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
65 Measles 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
66 Measles 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
67 Measles 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
68 Measles 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
69 Measles 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
70 Measles 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
71 Natural killer cell mediated cytotoxicity 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
72 Natural killer cell mediated cytotoxicity 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
73 Natural killer cell mediated cytotoxicity 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
74 Natural killer cell mediated cytotoxicity 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
75 Natural killer cell mediated cytotoxicity 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
76 Natural killer cell mediated cytotoxicity 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
77 Natural killer cell mediated cytotoxicity 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
78 Necroptosis 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
79 Necroptosis 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
80 Necroptosis 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
81 Necroptosis 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
82 Necroptosis 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
83 Necroptosis 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
84 Necroptosis 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
85 NOD-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
86 NOD-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
87 NOD-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
88 NOD-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
89 NOD-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
90 NOD-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
91 NOD-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
92 Osteoclast differentiation 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
93 Osteoclast differentiation 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
94 Osteoclast differentiation 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
95 Osteoclast differentiation 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
96 Osteoclast differentiation 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
97 Osteoclast differentiation 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
98 Osteoclast differentiation 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
99 Pathways in cancer 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
100 Pathways in cancer 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
101 Pathways in cancer 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
102 Pathways in cancer 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
103 Pathways in cancer 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
104 Pathways in cancer 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
105 Pathways in cancer 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
106 PI3K-Akt signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
107 PI3K-Akt signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
108 PI3K-Akt signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
109 PI3K-Akt signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
110 PI3K-Akt signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
111 PI3K-Akt signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
112 PI3K-Akt signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬
113 Toll-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab [3] 46, 49, 53 💬
114 Toll-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
115 Toll-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a [1] 56 💬
116 Toll-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b [2] 25, 34 💬
117 Toll-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
118 Toll-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b [1] 13 💬
119 Toll-like receptor signaling pathway 💬
[2] IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a [1] 13 💬