Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adherens junction 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
2 Adherens junction 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
3 Adherens junction 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
4 Aldosterone-regulated sodium reabsorption 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
5 Aldosterone-regulated sodium reabsorption 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
6 Aldosterone-regulated sodium reabsorption 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
7 Alzheimer disease 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
8 Alzheimer disease 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
9 Alzheimer disease 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
10 AMPK signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
11 AMPK signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
12 AMPK signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
13 cGMP-PKG signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
14 cGMP-PKG signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
15 cGMP-PKG signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
16 Diabetic cardiomyopathy 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
17 Diabetic cardiomyopathy 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
18 Diabetic cardiomyopathy 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
19 FoxO signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
20 FoxO signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
21 FoxO signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
22 HIF-1 signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
23 HIF-1 signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
24 HIF-1 signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
25 Insulin resistance 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
26 Insulin resistance 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
27 Insulin resistance 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
28 Insulin signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
29 Insulin signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
30 Insulin signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
31 Longevity regulating pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
32 Longevity regulating pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
33 Longevity regulating pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
34 Longevity regulating pathway - multiple species 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
35 Longevity regulating pathway - multiple species 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
36 Longevity regulating pathway - multiple species 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
37 MAPK signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
38 MAPK signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
39 MAPK signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
40 mTOR signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
41 mTOR signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
42 mTOR signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
43 Non-alcoholic fatty liver disease 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
44 Non-alcoholic fatty liver disease 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
45 Non-alcoholic fatty liver disease 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
46 Ovarian steroidogenesis 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
47 Ovarian steroidogenesis 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
48 Ovarian steroidogenesis 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
49 Phospholipase D signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
50 Phospholipase D signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
51 Phospholipase D signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
52 PI3K-Akt signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
53 PI3K-Akt signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
54 PI3K-Akt signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
55 Rap1 signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
56 Rap1 signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
57 Rap1 signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
58 Ras signaling pathway 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
59 Ras signaling pathway 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
60 Ras signaling pathway 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
61 Regulation of lipolysis in adipocytes 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
62 Regulation of lipolysis in adipocytes 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
63 Regulation of lipolysis in adipocytes 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬
64 Type II diabetes mellitus 💬
[1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
65 Type II diabetes mellitus 💬
[1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
66 Type II diabetes mellitus 💬
[1] INSR 💬 Insulin human 💬 Insulin human [2] 96, 156 💬