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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Adipocytokine signaling pathway 💬

[1] JAK2 💬

Baricitinib 💬

Baricitinib

[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
107	Juvenile idiopathic arthritis;JIA;
162	Pemphigoid;
265	Lipodystrophy;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
325	Hereditary autoinflammatory syndrome;

Adipocytokine signaling pathway 💬

[1] JAK2 💬

Peficitinib 💬

Peficitinib

[1] 46 💬

Adipocytokine signaling pathway 💬

[1] JAK2 💬

Ruxolitinib 💬

Ruxolitinib

[3] 60, 65, 228 💬

Adipocytokine signaling pathway 💬

[1] JAK2 💬

Tofacitinib 💬

Tofacitinib

[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬

Disease ID	Name
11	Myasthenia gravis;MG;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
65	Primary immunodeficiency;
84	Sarcoidosis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
300	IgG4-related disease;

AGE-RAGE signaling pathway in diabetic complications 💬

[1] JAK2 💬

Baricitinib 💬

Baricitinib

[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
107	Juvenile idiopathic arthritis;JIA;
162	Pemphigoid;
265	Lipodystrophy;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
325	Hereditary autoinflammatory syndrome;

AGE-RAGE signaling pathway in diabetic complications 💬

[1] JAK2 💬

Peficitinib 💬

Peficitinib

[1] 46 💬

AGE-RAGE signaling pathway in diabetic complications 💬

[1] JAK2 💬

Ruxolitinib 💬

Ruxolitinib

[3] 60, 65, 228 💬

AGE-RAGE signaling pathway in diabetic complications 💬

[1] JAK2 💬

Tofacitinib 💬

Tofacitinib

[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬

Disease ID	Name
11	Myasthenia gravis;MG;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
65	Primary immunodeficiency;
84	Sarcoidosis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
300	IgG4-related disease;

Chemical carcinogenesis - receptor activation 💬

[1] JAK2 💬

Baricitinib 💬

Baricitinib

[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
107	Juvenile idiopathic arthritis;JIA;
162	Pemphigoid;
265	Lipodystrophy;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
325	Hereditary autoinflammatory syndrome;

Chemical carcinogenesis - receptor activation 💬

[1] JAK2 💬

Peficitinib 💬

Peficitinib

[1] 46 💬

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