Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Cholinergic synapse 💬

[3] KCNJ12, KCNJ3, KCNQ1 💬

Amiodarone 💬

[2] 28, 127 💬

2

Circadian entrainment 💬

[2] KCNJ3, KCNJ5 💬

Amiodarone 💬

[2] 28, 127 💬

3

Dopaminergic synapse 💬

[3] KCNJ3, KCNJ5, SCN1A 💬

Amiodarone 💬

[2] 28, 127 💬

4

Estrogen signaling pathway 💬

[2] KCNJ3, KCNJ5 💬

Amiodarone 💬

[2] 28, 127 💬

5

Glutamatergic synapse 💬

[1] KCNJ3 💬

Amiodarone 💬

[2] 28, 127 💬

6

GnRH secretion 💬

[3] KCNJ11, KCNJ3, KCNJ5 💬

Name	Full Name
KCNJ11	potassium inwardly rectifying channel subfamily J member 11
KCNJ3	potassium inwardly rectifying channel subfamily J member 3
KCNJ5	potassium inwardly rectifying channel subfamily J member 5

Amiodarone 💬

[2] 28, 127 💬

7

Morphine addiction 💬

[2] KCNJ3, KCNJ5 💬

Amiodarone 💬

[2] 28, 127 💬

8

Oxytocin signaling pathway 💬

[3] KCNJ12, KCNJ3, KCNJ5 💬

Name	Full Name
KCNJ12	potassium inwardly rectifying channel subfamily J member 12
KCNJ3	potassium inwardly rectifying channel subfamily J member 3
KCNJ5	potassium inwardly rectifying channel subfamily J member 5

Amiodarone 💬

[2] 28, 127 💬

9

Retrograde endocannabinoid signaling 💬

[2] KCNJ3, KCNJ5 💬

Amiodarone 💬

[2] 28, 127 💬

10

Serotonergic synapse 💬

[2] KCNJ3, KCNJ5 💬

Amiodarone 💬

[2] 28, 127 💬

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