Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
2 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
3 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
4 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
5 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [6] FLT1, FLT4, KDR, PDGFRA, PDGFRB, RET 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
6 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT4 [4] FLT4, KDR, PDGFRB, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
7 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
8 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
AXL [3] AXL, KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
9 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BRAF [4] BRAF, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
10 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR [3] EGFR, ERBB2, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
11 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
FGFR2 [5] FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
12 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
KDR [1] KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
13 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
KDR [1] KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
14 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
KDR [3] KDR, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
15 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
16 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
17 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
18 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
19 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
20 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
21 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR [1] KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
22 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BRAF [5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
23 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
24 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
25 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
26 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
27 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
28 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
29 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
BRAF [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
30 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CSF1R [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
31 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
32 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
33 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
34 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
35 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
36 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF1R [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
37 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
38 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
39 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
40 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
41 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
42 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
43 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF [3] BRAF, KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
44 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR [3] EGFR, ERBB2, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
45 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
FGFR1 [2] FGFR1, KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
46 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
47 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
48 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [1] KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
49 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
50 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
BRAF [6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
51 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CSF1R [7] CSF1R, FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
52 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
EGFR [3] EGFR, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
53 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
54 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
55 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
56 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
57 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
CSF1R [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
58 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
EGFR [3] EGFR, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
59 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
60 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
61 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT1 [3] FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
62 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|
63 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
KDR [2] KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
64 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 [1] 34 💬
|
65 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 [1] 34 💬
|
66 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 [1] 34 💬
|
67 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬
|
68 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 [2] 28, 34 💬
|
69 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [1] KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 [1] 67 💬
|
70 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR [2] KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 [2] 34, 86 💬
|