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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Acute myeloid leukemia 💬

[4] BRAF, FLT3, KIT, RAF1 💬

Name	Full Name
BRAF	B-Raf proto-oncogene, serine/threonine kinase
FLT3	fms related receptor tyrosine kinase 3
KIT	KIT proto-oncogene, receptor tyrosine kinase
RAF1	Raf-1 proto-oncogene, serine/threonine kinase

Sorafenib 💬

Sorafenib

[2] 34, 86 💬

Acute myeloid leukemia 💬

[3] CSF1R, FLT3, KIT 💬

Pexidartinib 💬

Pexidartinib

[1] 34 💬

Acute myeloid leukemia 💬

[3] CSF1R, FLT3, KIT 💬

Sunitinib 💬

Sunitinib

[2] 28, 34 💬

Acute myeloid leukemia 💬

[1] KIT 💬

Dasatinib 💬

Dasatinib

[2] 51, 85 💬

Acute myeloid leukemia 💬

[1] KIT 💬

Dasatinib 💬

Dasatinib

[2] 51, 85 💬

Acute myeloid leukemia 💬

[1] KIT 💬

Imatinib 💬

Imatinib

[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
28	Systemic amyloidosis;AL amyloidosis;
34	Neurofibromatosis;
35	Pemphigus;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
86	Pulmonary arterial hypertension;PAH;
87	Pulmonary veno-occlusive disease;Pulmonary capillary hemangiomatosis;
88	Chronic thromboembolic pulmonary hypertension;CTEPH;Idiopathic chronic pulmonary thromboembolism;
89	Lymphangioleiomyomatosis;LAM;
162	Pemphigoid;

Acute myeloid leukemia 💬

[1] KIT 💬

Masitinib 💬

Masitinib

[6] 2 , 5 , 6 , 13, 46, 96 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
96	Crohn disease;Terminal ileitis;

Acute myeloid leukemia 💬

[1] KIT 💬

Nilotinib 💬

Nilotinib

[5] 6 , 8 , 34, 51, 86 💬

Breast cancer 💬

[4] BRAF, FLT4, KIT, RAF1 💬

Name	Full Name
BRAF	B-Raf proto-oncogene, serine/threonine kinase
FLT4	fms related receptor tyrosine kinase 4
KIT	KIT proto-oncogene, receptor tyrosine kinase
RAF1	Raf-1 proto-oncogene, serine/threonine kinase

Sorafenib 💬

Sorafenib

[2] 34, 86 💬

Breast cancer 💬

[2] FLT4, KIT 💬

Sunitinib 💬

Sunitinib

[2] 28, 34 💬

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