Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
3 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
4 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
5 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
6 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
7 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
8 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
9 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
10 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
11 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
12 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
13 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
14 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
15 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
16 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
17 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
18 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
19 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
20 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
21 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
22 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
23 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
24 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
25 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
26 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
27 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
28 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
29 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
30 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
31 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
32 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
33 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
34 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
35 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
36 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
37 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
38 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
39 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
40 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
41 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
42 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
43 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
44 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
45 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
46 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
47 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
48 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
49 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
50 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
51 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
52 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
53 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
54 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
55 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
56 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
57 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
58 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
59 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
60 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
61 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
62 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
63 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
64 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
65 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
66 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
67 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
68 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
69 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
70 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
71 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
72 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
73 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
74 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
75 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
76 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
77 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
78 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
79 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
80 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
81 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
82 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
83 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
84 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
85 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
86 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
87 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
88 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
89 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
90 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
91 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
92 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
93 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
94 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
95 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
96 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
97 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
98 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
99 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
100 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
101 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
102 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
103 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
104 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
105 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
106 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
107 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
108 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
109 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
110 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
111 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
112 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
113 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
114 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
115 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
116 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
117 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
118 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
119 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
120 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
121 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
122 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
123 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
124 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
125 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
126 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
127 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
128 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
129 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
130 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
131 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
132 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
133 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
134 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
135 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
136 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
137 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
138 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
139 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
140 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
141 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
142 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
143 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
144 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
145 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
146 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
147 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
148 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
149 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
150 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
151 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
152 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
153 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
154 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
155 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
156 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
157 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
158 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
159 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
160 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
161 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
162 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
163 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
164 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
165 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
166 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
167 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
168 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
169 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
170 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
171 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
172 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
173 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
174 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
175 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
176 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
177 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
178 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
179 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
180 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
181 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
182 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
183 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
184 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
185 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
186 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
187 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
188 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
189 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
190 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
191 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
192 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
193 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
194 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
195 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
196 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
197 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
198 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
199 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
200 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
201 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
202 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
203 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
204 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
205 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
206 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
207 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
208 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
209 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
210 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
211 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
212 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
213 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
214 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
215 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
216 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
217 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
218 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
219 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
220 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
221 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
222 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
223 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
224 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
225 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
226 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
227 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
228 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
229 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
230 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
231 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
232 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
233 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
234 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
235 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
236 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
237 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
238 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
239 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
240 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
241 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
242 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
243 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
244 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
245 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
246 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
247 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
248 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
249 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
250 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
251 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
252 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
253 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
254 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
255 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
256 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
257 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
258 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
259 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
260 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
261 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
262 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
263 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
264 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
265 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
266 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
267 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
268 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
269 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
270 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
271 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
272 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
273 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
274 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
275 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
276 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
277 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
278 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
279 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
280 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
281 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
282 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
283 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
284 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
285 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
286 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
287 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
288 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
289 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
290 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
291 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
292 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
293 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
294 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
295 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
296 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
297 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
298 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
299 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
300 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
301 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
302 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
303 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
304 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
305 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
306 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
307 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
308 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
309 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
310 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
311 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
312 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
313 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
314 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
315 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
316 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
317 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
318 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
319 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
320 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
321 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
322 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
323 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
324 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
325 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
326 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
327 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
328 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
329 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
330 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
331 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
332 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
333 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
334 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
335 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
336 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
337 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
338 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
339 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
340 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
341 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
342 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
343 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
344 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
345 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
346 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
347 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
348 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
349 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
350 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
351 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
352 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
353 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
354 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
355 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
356 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
357 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
358 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
359 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
360 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
361 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
362 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
363 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
364 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
365 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
366 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
367 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
368 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
369 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
370 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
371 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
372 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
373 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
374 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
375 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
376 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
377 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
378 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
379 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
380 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
381 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
382 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
383 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
384 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
385 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
386 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
387 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
388 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
389 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
390 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
391 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
392 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
393 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
394 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
395 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
396 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
397 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
398 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
399 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
400 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
401 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
402 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
403 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
404 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
405 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
406 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
407 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
408 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
409 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
410 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
411 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
412 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
413 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
414 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
415 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
416 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
417 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
418 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
419 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
420 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
421 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
422 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
423 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
424 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
425 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
MAP2K1 [1] MAP2K1 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
426 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
427 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
428 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
429 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
430 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
431 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
432 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
433 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
434 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
435 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
436 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
437 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
438 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
439 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
440 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|
441 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 [1] 34 💬
|
442 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 [1] 280 💬
|
443 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 [1] 34 💬
|
444 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 [1] 34 💬
|
445 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 [4] 2 , 34, 279, 280 💬
|