Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 cGMP-PKG signaling pathway 💬
[1] OPRD1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
2 cGMP-PKG signaling pathway 💬
[1] OPRD1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
3 cGMP-PKG signaling pathway 💬
[1] OPRD1 💬 Nalmefene 💬 Nalmefene [1]  6  💬
4 cGMP-PKG signaling pathway 💬
[1] OPRD1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
5 cGMP-PKG signaling pathway 💬
[1] OPRD1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
6 cGMP-PKG signaling pathway 💬
[1] OPRD1 💬 Oxycodone 💬 Oxycodone [5]  6 , 13, 70, 226, 298 💬
7 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
8 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
9 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Nalmefene 💬 Nalmefene [1]  6  💬
10 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
11 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
12 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Oxycodone 💬 Oxycodone [5]  6 , 13, 70, 226, 298 💬
13 Sphingolipid signaling pathway 💬
[1] OPRD1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
14 Sphingolipid signaling pathway 💬
[1] OPRD1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
15 Sphingolipid signaling pathway 💬
[1] OPRD1 💬 Nalmefene 💬 Nalmefene [1]  6  💬
16 Sphingolipid signaling pathway 💬
[1] OPRD1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
17 Sphingolipid signaling pathway 💬
[1] OPRD1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
18 Sphingolipid signaling pathway 💬
[1] OPRD1 💬 Oxycodone 💬 Oxycodone [5]  6 , 13, 70, 226, 298 💬