Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬
2 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬
3 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Nalmefene 💬 Nalmefene [1]  6  💬
4 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬
5 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
6 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Oxycodone 💬 Oxycodone [5]  6 , 13, 70, 226, 298 💬
7 Neuroactive ligand-receptor interaction 💬
[2] OPRK1, OPRM1 💬 Buprenorphine 💬 Buprenorphine [2] 46, 70 💬
8 Neuroactive ligand-receptor interaction 💬
[2] OPRK1, OPRM1 💬 Dezocine 💬 Dezocine [1] 46 💬
9 Neuroactive ligand-receptor interaction 💬
[2] OPRK1, OPRM1 💬 Trimebutine 💬 Trimebutine [1] 51 💬