Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Calcium signaling pathway 💬
 [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 Aminophylline 💬 Aminophylline [1] 63 💬
2 Calcium signaling pathway 💬
 [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
3 Calcium signaling pathway 💬
 [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
4 Calcium signaling pathway 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Bucladesine 💬 Bucladesine [1] 246 💬
5 Calcium signaling pathway 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Flavoxate 💬 Flavoxate [1] 226 💬
6 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
7 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
8 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
9 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
10 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
11 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
12 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
13 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
14 Morphine addiction 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
15 Morphine addiction 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
16 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 Aminophylline 💬 Aminophylline [1] 63 💬
17 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 Bucladesine 💬 Bucladesine [1] 246 💬
18 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 Flavoxate 💬 Flavoxate [1] 226 💬
19 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
20 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
21 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
22 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
23 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
24 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
25 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
26 Renin secretion 💬
 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Aminophylline 💬 Aminophylline [1] 63 💬
27 Renin secretion 💬
 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
28 Renin secretion 💬
 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
29 Renin secretion 💬
 [5] PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Bucladesine 💬 Bucladesine [1] 246 💬
30 Renin secretion 💬
 [5] PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Flavoxate 💬 Flavoxate [1] 226 💬
31 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Aminophylline 💬 Aminophylline [1] 63 💬
32 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Bucladesine 💬 Bucladesine [1] 246 💬
33 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Flavoxate 💬 Flavoxate [1] 226 💬
34 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
35 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬

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