Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
|---|---|---|---|---|---|
| 1 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 2 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 3 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Aminophylline Aminophylline 💬
| Aminophylline | 063 [1] 63 💬
|
| 4 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 5 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 6 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 7 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE10A [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Flavoxate Flavoxate 💬
| Flavoxate | 226 [1] 226 💬
|
| 8 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 9 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
| 10 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Roflumilast Roflumilast 💬
| Roflumilast | 084 [4] 84, 97, 206, 299 💬
|
| 11 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|
| 12 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Aminophylline Aminophylline 💬
| Aminophylline | 063 [1] 63 💬
|
| 13 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 14 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Flavoxate Flavoxate 💬
| Flavoxate | 226 [1] 226 💬
|
| 15 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 16 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 17 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 18 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 19 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 20 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
| 21 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Roflumilast Roflumilast 💬
| Roflumilast | 084 [4] 84, 97, 206, 299 💬
|
| 22 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|
| 23 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Aminophylline Aminophylline 💬
| Aminophylline | 063 [1] 63 💬
|
| 24 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 25 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 26 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 27 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 28 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 29 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Flavoxate Flavoxate 💬
| Flavoxate | 226 [1] 226 💬
|
| 30 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 31 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
| 32 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Roflumilast Roflumilast 💬
| Roflumilast | 084 [4] 84, 97, 206, 299 💬
|
| 33 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|
| 34 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Aminophylline Aminophylline 💬
| Aminophylline | 063 [1] 63 💬
|
| 35 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
| 36 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 37 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 38 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 39 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Flavoxate Flavoxate 💬
| Flavoxate | 226 [1] 226 💬
|
| 40 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 41 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Roflumilast Roflumilast 💬
| Roflumilast | 084 [4] 84, 97, 206, 299 💬
|
| 42 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|
| 43 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 44 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 45 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Aminophylline Aminophylline 💬
| Aminophylline | 063 [1] 63 💬
|
| 46 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Bucladesine Bucladesine 💬
| Bucladesine | 246 [1] 246 💬
|
| 47 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Flavoxate Flavoxate 💬
| Flavoxate | 226 [1] 226 💬
|
| 48 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 49 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬
|
Theophylline Theophylline 💬
| Theophylline | 236 [2] 236, 299 💬
|
| 50 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine Caffeine 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 51 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬
|
Caffeine hydrate Caffeine hydrate 💬
| Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
|
| 52 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Ibudilast Ibudilast 💬
| Ibudilast | 002 [2] 2 , 13 💬
|
| 53 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
| 54 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Roflumilast Roflumilast 💬
| Roflumilast | 084 [4] 84, 97, 206, 299 💬
|
| 55 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Rolipram Rolipram 💬
| Rolipram | 008 [2] 8 , 13 💬
|