Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Neuroactive ligand-receptor interaction 💬
[2] CYSLTR1, PTGIR 💬 Ibudilast 💬 Ibudilast [2]  2 , 13 💬
2 Neuroactive ligand-receptor interaction 💬
[1] PTGIR 💬 Beraprost 💬 Beraprost [1] 86 💬
3 Neuroactive ligand-receptor interaction 💬
[1] PTGIR 💬 Epoprostenol 💬 Epoprostenol [1] 86 💬
4 Neuroactive ligand-receptor interaction 💬
[1] PTGIR 💬 Iloprost 💬 Iloprost [4] 51, 84, 85, 86 💬
5 Neuroactive ligand-receptor interaction 💬
[1] PTGIR 💬 Ralinepag 💬 Ralinepag [1] 86 💬
6 Neuroactive ligand-receptor interaction 💬
[1] PTGIR 💬 Selexipag 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
7 Neuroactive ligand-receptor interaction 💬
[1] PTGIR 💬 Treprostinil 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
8 Platelet activation 💬
[1] PTGIR 💬 Beraprost 💬 Beraprost [1] 86 💬
9 Platelet activation 💬
[1] PTGIR 💬 Epoprostenol 💬 Epoprostenol [1] 86 💬
10 Platelet activation 💬
[1] PTGIR 💬 Ibudilast 💬 Ibudilast [2]  2 , 13 💬
11 Platelet activation 💬
[1] PTGIR 💬 Iloprost 💬 Iloprost [4] 51, 84, 85, 86 💬
12 Platelet activation 💬
[1] PTGIR 💬 Ralinepag 💬 Ralinepag [1] 86 💬
13 Platelet activation 💬
[1] PTGIR 💬 Selexipag 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
14 Platelet activation 💬
[1] PTGIR 💬 Treprostinil 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
15 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 Beraprost 💬 Beraprost [1] 86 💬
16 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 Epoprostenol 💬 Epoprostenol [1] 86 💬
17 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 Ibudilast 💬 Ibudilast [2]  2 , 13 💬
18 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 Iloprost 💬 Iloprost [4] 51, 84, 85, 86 💬
19 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 Ralinepag 💬 Ralinepag [1] 86 💬
20 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 Selexipag 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
21 Vascular smooth muscle contraction 💬
[1] PTGIR 💬 Treprostinil 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬