Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Taste transduction 💬
[10] CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 Topiramate 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
2 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Amiodarone 💬 Amiodarone [2] 28, 127 💬
3 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Bupivacaine 💬 Bupivacaine [8] 46, 51, 53, 70, 96, 168, 226, 298 💬
4 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Carbamazepine 💬 Carbamazepine [3]  6 , 13, 231 💬
5 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Cifenline 💬 Cibenzoline [1] 58 💬
6 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Eleclazine 💬 Eleclazine [1] 58 💬
7 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Flecainide 💬 Flecainide [1]  6  💬
8 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Lamotrigine 💬 Lamotrigine [5] 13, 34, 38, 114, 144 💬
9 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Levobupivacaine 💬 Levobupivacaine [1] 46 💬
10 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Lidocaine 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
11 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Lidocaine hydrochloride monohydrate 💬 Lidocaine [13]  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
12 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬
13 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Oxcarbazepine 💬 Oxcarbazepine [1] 13 💬
14 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Oxybuprocaine 💬 Oxybuprocaine [1]  6  💬
15 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Phenytoin 💬 Phenytoin [1] 13 💬
16 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Quinidine 💬 Quinidine [3]  2 ,  8 , 13 💬
17 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Ropivacaine 💬 Ropivacaine [4] 22, 36, 46, 70 💬
18 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Rufinamide 💬 Rufinamide [1] 144 💬
19 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Zonisamide 💬 Zonisamide [1]  6  💬