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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Taste transduction 💬

[10] CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬

Name	Full Name
CACNA1C	calcium voltage-gated channel subunit alpha1 C
GABRA1	gamma-aminobutyric acid type A receptor subunit alpha1
GABRA2	gamma-aminobutyric acid type A receptor subunit alpha2
GABRA3	gamma-aminobutyric acid type A receptor subunit alpha3
GABRA4	gamma-aminobutyric acid type A receptor subunit alpha4
GABRA5	gamma-aminobutyric acid type A receptor subunit alpha5
GABRA6	gamma-aminobutyric acid type A receptor subunit alpha6
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN9A	sodium voltage-gated channel alpha subunit 9

Topiramate 💬

Topiramate

[6] 6 , 97, 140, 144, 156, 193 💬

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Amiodarone 💬

Amiodarone

[2] 28, 127 💬

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Bupivacaine 💬

Bupivacaine

[8] 46, 51, 53, 70, 96, 168, 226, 298 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
70	Spinal stenosis;Extensive spinal canal stenosis;
96	Crohn disease;Terminal ileitis;
168	Ehlers-Danlos syndrome;EDS;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
298	Hereditary pancreatitis;Chronic pancreatitis;

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Carbamazepine 💬

Carbamazepine

[3] 6 , 13, 231 💬

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Cifenline 💬

Cibenzoline

[1] 58 💬

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Eleclazine 💬

Eleclazine

[1] 58 💬

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Flecainide 💬

Flecainide

[1] 6 💬

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Lamotrigine 💬

Lamotrigine

[5] 13, 34, 38, 114, 144 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
34	Neurofibromatosis;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
114	Non-dystrophic myotonia syndrome;Non-dystrophic Myotonia;
144	Lennox-Gastaut syndrome;

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Levobupivacaine 💬

Levobupivacaine

[1] 46 💬

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Lidocaine 💬

Lidocaine

[13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
22	Moyamoya disease;Occlusive disease in circle of Willis;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
70	Spinal stenosis;Extensive spinal canal stenosis;
84	Sarcoidosis;
86	Pulmonary arterial hypertension;PAH;
107	Juvenile idiopathic arthritis;JIA;
168	Ehlers-Danlos syndrome;EDS;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
256	Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;

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