Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Serotonergic synapse 💬
 [7] HTR1A, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E, SLC6A4 💬 Vortioxetine 💬 Vortioxetine [1]  6  💬
2 Serotonergic synapse 💬
 [4] HTR1D, HTR2A, HTR2C, SLC6A4 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
3 Serotonergic synapse 💬
 [4] HTR2A, HTR2B, HTR2C, SLC6A4 💬 Trazodone 💬 Trazodone [1]  2  💬
4 Serotonergic synapse 💬
 [3] MAOA, MAOB, SLC6A4 💬 Phentermine 💬 Phentermine [1] 97 💬
5 Serotonergic synapse 💬
 [1] SLC6A4 💬 Amitriptyline 💬 Amitriptyline [4] 78, 97, 226, 299 💬
6 Serotonergic synapse 💬
 [1] SLC6A4 💬 Amoxapine 💬 Amoxapine [1] 46 💬
7 Serotonergic synapse 💬
 [1] SLC6A4 💬 Ampreloxetine 💬 Ampreloxetine [2]  6 , 17 💬
8 Serotonergic synapse 💬
 [1] SLC6A4 💬 Citalopram 💬 Citalopram [7]  6 ,  8 , 13, 18, 46, 98, 127 💬
9 Serotonergic synapse 💬
 [1] SLC6A4 💬 Desipramine 💬 Desipramine [2] 120, 156 💬
10 Serotonergic synapse 💬
 [1] SLC6A4 💬 Doxepin 💬 Doxepin [1]  6  💬
11 Serotonergic synapse 💬
 [1] SLC6A4 💬 Duloxetine 💬 Duloxetine [2]  6 , 13 💬
12 Serotonergic synapse 💬
 [1] SLC6A4 💬 Escitalopram 💬 Escitalopram [4]  2 ,  6 , 13, 46 💬
13 Serotonergic synapse 💬
 [1] SLC6A4 💬 Fluoxetine 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬
14 Serotonergic synapse 💬
 [1] SLC6A4 💬 Milnacipran 💬 Milnacipran [2] 46, 49 💬
15 Serotonergic synapse 💬
 [1] SLC6A4 💬 Nortriptyline 💬 Nortriptyline [2]  6 , 226 💬
16 Serotonergic synapse 💬
 [1] SLC6A4 💬 Paroxetine 💬 Paroxetine [4]  6 , 13, 46, 85 💬
17 Serotonergic synapse 💬
 [1] SLC6A4 💬 Sertraline 💬 Sertraline [2]  6 , 206 💬
18 Serotonergic synapse 💬
 [1] SLC6A4 💬 Venlafaxine 💬 Venlafaxine [3]  6 , 13, 46 💬
19 Synaptic vesicle cycle 💬
 [3] SLC6A2, SLC6A3, SLC6A4 💬 Phentermine 💬 Phentermine [1] 97 💬
20 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Amitriptyline 💬 Amitriptyline [4] 78, 97, 226, 299 💬
21 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Amoxapine 💬 Amoxapine [1] 46 💬
22 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Ampreloxetine 💬 Ampreloxetine [2]  6 , 17 💬
23 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Desipramine 💬 Desipramine [2] 120, 156 💬
24 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Doxepin 💬 Doxepin [1]  6  💬
25 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Duloxetine 💬 Duloxetine [2]  6 , 13 💬
26 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Milnacipran 💬 Milnacipran [2] 46, 49 💬
27 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Nortriptyline 💬 Nortriptyline [2]  6 , 226 💬
28 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Venlafaxine 💬 Venlafaxine [3]  6 , 13, 46 💬
29 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Citalopram 💬 Citalopram [7]  6 ,  8 , 13, 18, 46, 98, 127 💬
30 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Escitalopram 💬 Escitalopram [4]  2 ,  6 , 13, 46 💬
31 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Fenfluramine 💬 Fenfluramine [4] 140, 144, 145, 149 💬
32 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Fluoxetine 💬 Fluoxetine [6] 13, 17, 78, 86, 179, 206 💬
33 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Paroxetine 💬 Paroxetine [4]  6 , 13, 46, 85 💬
34 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Sertraline 💬 Sertraline [2]  6 , 206 💬
35 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Trazodone 💬 Trazodone [1]  2  💬
36 Synaptic vesicle cycle 💬
 [1] SLC6A4 💬 Vortioxetine 💬 Vortioxetine [1]  6  💬

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