Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Insulin secretion 💬

[1] SNAP25 💬

Botulinum toxin type A 💬

Botulinum toxin type A

[14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;
7	Corticobasal degeneration;Corticobasal syndrome;CBD;
13	Multiple sclerosis/Neuromyelitis optica;
15	Inclusion body myositis;
17	Multiple system atrophy;MSA-C;MSA-P;
36	Epidermolysis bullosa;
47	Buerger disease;Thromboangiitis obliterans;
51	Scleroderma;Systemic sclerosis;SSc;
70	Spinal stenosis;Extensive spinal canal stenosis;
113	Muscular dystrophy;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

2

Insulin secretion 💬

[1] SNAP25 💬

Rimabotulinumtoxin B 💬

Botulinum toxin type B

[4] 2 , 6 , 13, 51 💬

3

Synaptic vesicle cycle 💬

[1] SNAP25 💬

Botulinum toxin type A 💬

Botulinum toxin type A

[14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;
7	Corticobasal degeneration;Corticobasal syndrome;CBD;
13	Multiple sclerosis/Neuromyelitis optica;
15	Inclusion body myositis;
17	Multiple system atrophy;MSA-C;MSA-P;
36	Epidermolysis bullosa;
47	Buerger disease;Thromboangiitis obliterans;
51	Scleroderma;Systemic sclerosis;SSc;
70	Spinal stenosis;Extensive spinal canal stenosis;
113	Muscular dystrophy;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

4

Synaptic vesicle cycle 💬

[1] SNAP25 💬

Rimabotulinumtoxin B 💬

Botulinum toxin type B

[4] 2 , 6 , 13, 51 💬