Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adherens junction 💬
 [3] FYN, SRC, YES1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
2 Adherens junction 💬
 [3] FYN, SRC, YES1 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
3 Adherens junction 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
4 Adherens junction 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
5 Axon guidance 💬
 [4] ABL1, EPHA2, FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
6 Axon guidance 💬
 [4] ABL1, EPHA2, FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
7 Axon guidance 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
8 Axon guidance 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
9 Bacterial invasion of epithelial cells 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
10 Bacterial invasion of epithelial cells 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
11 Bacterial invasion of epithelial cells 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
12 Bacterial invasion of epithelial cells 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
13 Bladder cancer 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
14 Bladder cancer 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
15 Bladder cancer 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
16 Bladder cancer 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
17 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
18 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
19 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
20 C-type lectin receptor signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
21 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
22 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
23 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
24 Chemical carcinogenesis - reactive oxygen species 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
25 Chemical carcinogenesis - receptor activation 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
26 Chemical carcinogenesis - receptor activation 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
27 Chemical carcinogenesis - receptor activation 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
28 Chemical carcinogenesis - receptor activation 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
29 Chemokine signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
30 Chemokine signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
31 Chemokine signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
32 Chemokine signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
33 EGFR tyrosine kinase inhibitor resistance 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
34 EGFR tyrosine kinase inhibitor resistance 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
35 EGFR tyrosine kinase inhibitor resistance 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
36 EGFR tyrosine kinase inhibitor resistance 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
37 Endocrine resistance 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
38 Endocrine resistance 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
39 Endocrine resistance 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
40 Endocrine resistance 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
41 Endocytosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
42 Endocytosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
43 Endocytosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
44 Endocytosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
45 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
46 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
47 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
48 Epithelial cell signaling in Helicobacter pylori infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
49 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
50 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
51 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
52 ErbB signaling pathway 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
53 Estrogen signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
54 Estrogen signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
55 Estrogen signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
56 Estrogen signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
57 Fluid shear stress and atherosclerosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
58 Fluid shear stress and atherosclerosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
59 Fluid shear stress and atherosclerosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
60 Fluid shear stress and atherosclerosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
61 Focal adhesion 💬
 [3] FYN, PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
62 Focal adhesion 💬
 [3] FYN, PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
63 Focal adhesion 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
64 Focal adhesion 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
65 GABAergic synapse 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
66 GABAergic synapse 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
67 GABAergic synapse 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
68 GABAergic synapse 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
69 Gap junction 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
70 Gap junction 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
71 Gap junction 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
72 Gap junction 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
73 GnRH signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
74 GnRH signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
75 GnRH signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
76 GnRH signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
77 Hepatitis B 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
78 Hepatitis B 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
79 Hepatitis B 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
80 Hepatitis B 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
81 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
82 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
83 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
84 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
85 Human cytomegalovirus infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
86 Human cytomegalovirus infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
87 Human cytomegalovirus infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
88 Human cytomegalovirus infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
89 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
90 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
91 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
92 Inflammatory mediator regulation of TRP channels 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
93 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
94 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
95 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
96 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
97 Lipid and atherosclerosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
98 Lipid and atherosclerosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
99 Lipid and atherosclerosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
100 Lipid and atherosclerosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
101 Mitophagy - animal 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
102 Mitophagy - animal 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
103 Mitophagy - animal 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
104 Mitophagy - animal 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
105 Neutrophil extracellular trap formation 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
106 Neutrophil extracellular trap formation 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
107 Neutrophil extracellular trap formation 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
108 Neutrophil extracellular trap formation 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
109 Oxytocin signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
110 Oxytocin signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
111 Oxytocin signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
112 Oxytocin signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
113 Pathogenic Escherichia coli infection 💬
 [3] ABL1, FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
114 Pathogenic Escherichia coli infection 💬
 [3] ABL1, FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
115 Pathogenic Escherichia coli infection 💬
 [2] ABL1, SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
116 Pathogenic Escherichia coli infection 💬
 [2] ABL1, SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
117 Platelet activation 💬
 [2] FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
118 Platelet activation 💬
 [2] FYN, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
119 Platelet activation 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
120 Platelet activation 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
121 Prolactin signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
122 Prolactin signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
123 Prolactin signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
124 Prolactin signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
125 Proteoglycans in cancer 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
126 Proteoglycans in cancer 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
127 Proteoglycans in cancer 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
128 Proteoglycans in cancer 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
129 Rap1 signaling pathway 💬
 [4] EPHA2, KIT, PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
130 Rap1 signaling pathway 💬
 [4] EPHA2, KIT, PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
131 Rap1 signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
132 Rap1 signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
133 Regulation of actin cytoskeleton 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
134 Regulation of actin cytoskeleton 💬
 [2] PDGFRB, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
135 Regulation of actin cytoskeleton 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
136 Regulation of actin cytoskeleton 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
137 Relaxin signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
138 Relaxin signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
139 Relaxin signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
140 Relaxin signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
141 Shigellosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
142 Shigellosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
143 Shigellosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
144 Shigellosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
145 Thyroid hormone signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
146 Thyroid hormone signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
147 Thyroid hormone signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
148 Thyroid hormone signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
149 Tight junction 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
150 Tight junction 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
151 Tight junction 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
152 Tight junction 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
153 Tuberculosis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
154 Tuberculosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
155 Tuberculosis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
156 Tuberculosis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
157 VEGF signaling pathway 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
158 VEGF signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
159 VEGF signaling pathway 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
160 VEGF signaling pathway 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
161 Viral carcinogenesis 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
162 Viral carcinogenesis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
163 Viral carcinogenesis 💬
 [1] SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
164 Viral carcinogenesis 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬
165 Yersinia infection 💬
 [2] LCK, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
166 Yersinia infection 💬
 [2] LCK, SRC 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
167 Yersinia infection 💬
 [1] SRC 💬 Bosutinib 💬 Bosutinib [2]  2 , 67 💬
168 Yersinia infection 💬
 [1] SRC 💬 Saracatinib 💬 Saracatinib [3]  6 , 89, 272 💬

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