Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Tyrosine metabolism 💬

[3] ADH1A, ADH1B, ADH1C 💬

Fomepizole 💬

[1] 301 💬

2

Tyrosine metabolism 💬

[1] AOC3 💬

Hydralazine 💬

[1] 67 💬

3

Tyrosine metabolism 💬

[1] COMT 💬

Entacapone 💬

[2] 6 , 17 💬

4

Tyrosine metabolism 💬

[1] COMT 💬

[1] 6 💬

5

Tyrosine metabolism 💬

[1] COMT 💬

[3] 6 , 28, 127 💬

6

Tyrosine metabolism 💬

[1] DDC 💬

Benserazide 💬

[1] 6 💬

7

Tyrosine metabolism 💬

[1] DDC 💬

[7] 6 , 13, 17, 90, 140, 164, 201 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
17	Multiple system atrophy;MSA-C;MSA-P;
90	Retinitis pigmentosa;
140	Dorabe syndrome;Dravet syndrome;
164	Oculocutaneous albinism;
201	Angelman syndrome;

8

Tyrosine metabolism 💬

[1] HPD 💬

Nitisinone 💬

[3] 6 , 164, 241 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
164	Oculocutaneous albinism;
241	Hypertyrosinemia type I;Tyrosinemia type I;Tyrosinemia I;Hereditary tyrosinemia, Type I;Fumarylacetoacetate hydrolase deficiency;FAH deficiency;

9

Tyrosine metabolism 💬

[1] MAOA 💬

Moclobemide 💬

[1] 6 💬

10

Tyrosine metabolism 💬

[2] MAOA, MAOB 💬

Iproniazid 💬

[1] 6 💬

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