Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ABAT [1] ABAT 💬 |
Vigabatrin Vigabatrin 💬 |
Vigabatrin | 145 [2] 145, 158 💬 💬 |
2 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
3 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
Fomepizole Fomepizole 💬 |
Fomepizole | 301 [1] 301 💬 💬 |
4 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALAS1 [1] ALAS1 💬 |
Givosiran Givosiran 💬 |
Givosiran | 254 [1] 254 💬 💬 |
5 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALAS1 [2] ALAS1, ALAS2 💬 |
Hemin Hemin 💬 |
Hemin | 254 [1] 254 💬 💬 |
6 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALOX5 [1] ALOX5 💬 |
Oxatomide Oxatomide 💬 |
Oxatomide | 113 [1] 113 💬 💬 |
7 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALOX5 [1] ALOX5 💬 |
Zileuton Zileuton 💬 |
Zileuton | 085 [3] 85, 160, 164 💬 💬 |
8 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ALPL [1] ALPL 💬 |
Asfotase alfa Asfotase alfa 💬 |
Asfotase alfa | 172 [1] 172 💬 💬 |
9 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
AMY2A [5] AMY2A, AMY2B, GAA, GANC, MGAM 💬 |
Acarbose Acarbose 💬 |
Acarbose | 298 [1] 298 💬 💬 |
10 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ANPEP [1] ANPEP 💬 |
Ubenimex Ubenimex 💬 |
Ubenimex | 086 [1] 86 💬 💬 |
11 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
AOC3 [1] AOC3 💬 |
Hydralazine Hydralazine 💬 |
Hydralazine | 067 [1] 67 💬 💬 |
12 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ARSB [1] ARSB 💬 |
Galsulfase Galsulfase 💬 |
Galsulfase | 019 [1] 19 💬 💬 |
13 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Dexlansoprazole Dexlansoprazole 💬 |
Dexlansoprazole | 098 [1] 98 💬 💬 |
14 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Esomeprazole Esomeprazole 💬 |
Esomeprazole | 013 [8] 13, 46, 86, 98, 107, 113, 298, 299 💬 💬 |
15 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Lansoprazole Lansoprazole 💬 |
Lansoprazole | 063 [7] 63, 71, 85, 98, 166, 222, 299 💬 💬 |
16 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Omeprazole Omeprazole 💬 |
Omeprazole | 006 [14] 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 💬 |
17 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Pantoprazole Pantoprazole 💬 |
Pantoprazole | 013 [2] 13, 65 💬 💬 |
18 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Rabeprazole Rabeprazole 💬 |
Rabeprazole | 002 [2] 2 , 51 💬 💬 |
19 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A [2] ATP4A, ATP4B 💬 |
Vonoprazan Vonoprazan 💬 |
Vonoprazan | 063 [2] 63, 98 💬 💬 |
20 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
Acetazolamide Acetazolamide 💬 |
Acetazolamide | 013 [8] 13, 86, 90, 115, 154, 155, 225, 230 💬 💬 |
21 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
Dichlorphenamide Dichlorphenamide 💬 |
Diclofenamide | 114 [1] 114 💬 💬 |
22 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
Dorzolamide Dorzolamide 💬 |
Dorzolamide | 090 [1] 90 💬 💬 |
23 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CA2 [2] CA2, CA4 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
24 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CD38 [1] CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 [5] 13, 28, 48, 49, 63 💬 💬 |
25 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CD38 [1] CD38 💬 |
Isatuximab Isatuximab 💬 |
Isatuximab | 028 [3] 28, 61, 283 💬 💬 |
26 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CD38 [1] CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 [2] 63, 66 💬 💬 |
27 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
COMT [1] COMT 💬 |
Entacapone Entacapone 💬 |
Entacapone | 006 [2] 6 , 17 💬 💬 |
28 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
COMT [1] COMT 💬 |
Opicapone Opicapone 💬 |
Opicapone | 006 [1] 6 💬 💬 |
29 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
COMT [1] COMT 💬 |
Tolcapone Tolcapone 💬 |
Tolcapone | 006 [3] 6 , 28, 127 💬 💬 |
30 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CPS1 [1] CPS1 💬 |
Carglumic acid Carglumic acid 💬 |
Carglumic acid | 245 [3] 245, 246, 251 💬 💬 |
31 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP11A1 [3] CYP11A1, CYP11B1, CYP17A1 💬 |
Levoketoconazole Levoketoconazole 💬 |
Levoketoconazole | 075 [1] 75 💬 💬 |
32 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP11B1 [1] CYP11B1 💬 |
Metyrapone Metyrapone 💬 |
Metyrapone | 075 [1] 75 💬 💬 |
33 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP11B2 [1] CYP11B2 💬 |
Osilodrostat Osilodrostat 💬 |
Osilodrostat | 075 [1] 75 💬 💬 |
34 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP17A1 [1] CYP17A1 💬 |
Ketoconazole Ketoconazole 💬 |
Ketoconazole | 008 [3] 8 , 13, 75 💬 💬 |
35 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP19A1 [1] CYP19A1 💬 |
Anastrozole Anastrozole 💬 |
Anastrozole | 078 [3] 78, 86, 193 💬 💬 |
36 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CYP19A1 [1] CYP19A1 💬 |
Letrozole Letrozole 💬 |
Letrozole | 081 [2] 81, 89 💬 💬 |
37 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DDC [1] DDC 💬 |
Benserazide Benserazide 💬 |
Benserazide | 006 [1] 6 💬 💬 |
38 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DDC [1] DDC 💬 |
Carbidopa Carbidopa 💬 |
Carbidopa | 006 [7] 6 , 13, 17, 90, 140, 164, 201 💬 💬 |
39 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHFR [2] DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
40 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHODH [1] DHODH 💬 |
Leflunomide Leflunomide 💬 |
Leflunomide | 011 [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 💬 |
41 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHODH [1] DHODH 💬 |
Teriflunomide Teriflunomide 💬 |
Teriflunomide | 013 [3] 13, 25, 26 💬 💬 |
42 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DNMT1 [3] DNMT1, DNMT3A, DNMT3B 💬 |
Decitabine Decitabine 💬 |
Decitabine | 013 [3] 13, 60, 63 💬 💬 |
43 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ENPP2 [1] ENPP2 💬 |
Ziritaxestat Ziritaxestat 💬 |
Ziritaxestat | 051 [2] 51, 85 💬 💬 |
44 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Alendronic acid Alendronic acid 💬 |
Alendronic acid | 019 [7] 19, 41, 46, 50, 271, 274, 299 💬 💬 |
45 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Pamidronic acid Pamidronic acid 💬 |
Pamidronic acid | 270 [3] 270, 271, 274 💬 💬 |
46 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Risedronic acid Risedronic acid 💬 |
Risedronic acid | 046 [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 💬 |
47 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Zoledronic acid Zoledronic acid 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 💬 |
48 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
FDPS [1] FDPS 💬 |
Zoledronic acid Zoledronic acid 💬 |
Zoledronic acid | 005 [13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 💬 |
49 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GAA [1] GAA 💬 |
Alglucosidase alfa Alglucosidase alfa 💬 |
Alglucosidase alfa | 256 [1] 256 💬 💬 |
50 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GAA [1] GAA 💬 |
Avalglucosidase alfa Avalglucosidase alfa 💬 |
Avalglucosidase alfa | 256 [1] 256 💬 💬 |
51 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GAA [1] GAA 💬 |
Cipaglucosidase alfa Cipaglucosidase alfa 💬 |
Cipaglucosidase alfa | 256 [1] 256 💬 💬 |
52 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GAA [1] GAA 💬 |
Duvoglustat Duvoglustat 💬 |
Duvoglustat | 256 [1] 256 💬 💬 |
53 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GALNS [1] GALNS 💬 |
Elosulfase alfa Elosulfase alfa 💬 |
Elosulfase alfa | 019 [1] 19 💬 💬 |
54 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GBA1 [1] GBA1 💬 |
Alglucerase Alglucerase 💬 |
Alglucerase | 019 [1] 19 💬 💬 |
55 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GBA1 [1] GBA1 💬 |
Imiglucerase Imiglucerase 💬 |
Imiglucerase | 019 [1] 19 💬 💬 |
56 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GBA1 [1] GBA1 💬 |
Taliglucerase alfa Taliglucerase alfa 💬 |
Taliglucerase alfa | 019 [1] 19 💬 💬 |
57 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GBA1 [1] GBA1 💬 |
Velaglucerase alfa Velaglucerase alfa 💬 |
Velaglucerase alfa | 019 [1] 19 💬 💬 |
58 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GLA [1] GLA 💬 |
Agalsidase alfa Agalsidase alfa 💬 |
Agalsidase alfa | 019 [1] 19 💬 💬 |
59 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GLA [1] GLA 💬 |
Agalsidase beta Agalsidase beta 💬 |
Agalsidase beta | 019 [1] 19 💬 💬 |
60 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Amyl nitrite Amyl nitrite 💬 |
Amyl Nitrite | 058 [1] 58 💬 💬 |
61 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 💬 |
62 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GUCY2C [1] GUCY2C 💬 |
Linaclotide Linaclotide 💬 |
Linaclotide | 006 [2] 6 , 97 💬 💬 |
63 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GUSB [1] GUSB 💬 |
Vestronidase alfa Vestronidase alfa 💬 |
Vestronidase alfa | 019 [1] 19 💬 💬 |
64 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HAO1 [1] HAO1 💬 |
Lumasiran Lumasiran 💬 |
Lumasiran | 234 [1] 234 💬 💬 |
65 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
66 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Fluvastatin Fluvastatin 💬 |
Fluvastatin | 079 [3] 79, 218, 222 💬 💬 |
67 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Lovastatin Lovastatin 💬 |
Lovastatin | 006 [11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 💬 |
68 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Pravastatin Pravastatin 💬 |
Pravastatin | 013 [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 💬 |
69 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Rosuvastatin Rosuvastatin 💬 |
Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 💬 |
70 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 [21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
71 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMOX1 [2] HMOX1, HMOX2 💬 |
Stannsoporfin Stannsoporfin 💬 |
Stannsoporfin | 254 [1] 254 💬 💬 |
72 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HPD [1] HPD 💬 |
Nitisinone Nitisinone 💬 |
Nitisinone | 006 [3] 6 , 164, 241 💬 💬 |
73 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HPRT1 [1] HPRT1 💬 |
Mercaptopurine Mercaptopurine 💬 |
Mercaptopurine | 065 [4] 65, 96, 97, 164 💬 💬 |
74 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HPRT1 [1] HPRT1 💬 |
Mercaptopurine Mercaptopurine 💬 |
Mercaptopurine | 065 [4] 65, 96, 97, 164 💬 💬 |
75 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HPRT1 [1] HPRT1 💬 |
Tioguanine Tioguanine 💬 |
Tioguanine | 013 [2] 13, 37 💬 💬 |
76 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IDS [1] IDS 💬 |
Idursulfase Idursulfase 💬 |
Idursulfase | 019 [1] 19 💬 💬 |
77 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IDS [1] IDS 💬 |
Idursulfase beta Idursulfase beta 💬 |
Idursulfase beta | 019 [1] 19 💬 💬 |
78 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IDS [1] IDS 💬 |
Pabinafusp alfa Pabinafusp alfa 💬 |
Pabinafusp alfa | 019 [1] 19 💬 💬 |
79 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IDUA [1] IDUA 💬 |
Laronidase Laronidase 💬 |
Laronidase | 019 [2] 19, 256 💬 💬 |
80 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Mizoribine Mizoribine 💬 |
Mizoribine | 046 [8] 46, 49, 51, 53, 66, 94, 222, 224 💬 💬 |
81 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Mycophenolate mofetil Mycophenolate mofetil 💬 |
Mycophenolate mofetil | 002 [34] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 💬 |
82 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 [2] IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 [36] 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
83 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOA [1] MAOA 💬 |
Moclobemide Moclobemide 💬 |
Moclobemide | 006 [1] 6 💬 💬 |
84 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOA [2] MAOA, MAOB 💬 |
Iproniazid Iproniazid 💬 |
Iproniazid | 006 [1] 6 💬 💬 |
85 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOA [2] MAOA, MAOB 💬 |
Phenelzine Phenelzine 💬 |
Phenelzine | 006 [1] 6 💬 💬 |
86 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOA [2] MAOA, MAOB 💬 |
Phentermine Phentermine 💬 |
Phentermine | 097 [1] 97 💬 💬 |
87 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬 |
Rasagiline Rasagiline 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
88 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬 |
Rasagiline tartrate Rasagiline tartrate 💬 |
Rasagiline | 002 [6] 2 , 5 , 6 , 17, 58, 66 💬 💬 |
89 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬 |
Safinamide Safinamide 💬 |
Safinamide | 006 [2] 6 , 17 💬 💬 |
90 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
MAOB [1] MAOB 💬 |
Selegiline Selegiline 💬 |
Selegiline | 006 [1] 6 💬 💬 |
91 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NPR1 [1] NPR1 💬 |
Nesiritide Nesiritide 💬 |
Nesiritide | 046 [2] 46, 58 💬 💬 |
92 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NPR1 [2] NPR1, NPR2 💬 |
Erythrityl tetranitrate Erythrityl tetranitrate 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 💬 |
93 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NPR2 [1] NPR2 💬 |
Vosoritide Vosoritide 💬 |
Vosoritide | 276 [1] 276 💬 💬 |
94 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
NQO1 [2] NQO1, VKORC1 💬 |
Warfarin Warfarin 💬 |
Warfarin | 006 [11] 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 💬 |
95 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ODC1 [1] ODC1 💬 |
Eflornithine Eflornithine 💬 |
Eflornithine | 065 [1] 65 💬 💬 |
96 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PAH [1] PAH 💬 |
Pegvaliase Pegvaliase 💬 |
Pegvaliase | 240 [1] 240 💬 💬 |
97 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 [1] 63 💬 💬 |
98 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Bucladesine Bucladesine 💬 |
Bucladesine | 246 [1] 246 💬 💬 |
99 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Flavoxate Flavoxate 💬 |
Flavoxate | 226 [1] 226 💬 💬 |
100 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
101 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Theophylline Theophylline 💬 |
Theophylline | 236 [2] 236, 299 💬 💬 |
102 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
103 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
104 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Cilostazol Cilostazol 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 💬 |
105 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Levosimendan Levosimendan 💬 |
Levosimendan | 002 [1] 2 💬 💬 |
106 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [2] PDE3A, PDE3B 💬 |
Milrinone Milrinone 💬 |
Milrinone | 294 [1] 294 💬 💬 |
107 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE3A [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Ibudilast Ibudilast 💬 |
Ibudilast | 002 [2] 2 , 13 💬 💬 |
108 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Apremilast Apremilast 💬 |
Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬 💬 |
109 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 [4] 84, 97, 206, 299 💬 💬 |
110 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Rolipram Rolipram 💬 |
Rolipram | 008 [2] 8 , 13 💬 💬 |
111 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [2] PDE4A, PDE5A 💬 |
Dipyridamole Dipyridamole 💬 |
Dipyridamole | 046 [6] 46, 49, 51, 66, 96, 224 💬 💬 |
112 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4D [1] PDE4D 💬 |
Zatolmilast Zatolmilast 💬 |
Zatolmilast | 206 [1] 206 💬 💬 |
113 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬 |
Sildenafil Sildenafil 💬 |
Sildenafil | 006 [17] 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 💬 |
114 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬 |
Tadalafil Tadalafil 💬 |
Tadalafil | 006 [7] 6 , 51, 75, 84, 86, 113, 210 💬 💬 |
115 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬 |
Udenafil Udenafil 💬 |
Udenafil | 086 [2] 86, 210 💬 💬 |
116 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A [1] PDE5A 💬 |
Vardenafil Vardenafil 💬 |
Vardenafil | 013 [3] 13, 86, 299 💬 💬 |
117 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
118 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
119 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
120 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGES [3] PTGES, PTGS1, PTGS2 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 [1] 46 💬 💬 |
121 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
122 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
123 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 💬 |
124 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 💬 |
125 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 💬 |
126 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 💬 |
127 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 [1] 46 💬 💬 |
128 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 [2] 70, 226 💬 💬 |
129 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 [2] 46, 271 💬 💬 |
130 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 💬 |
131 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 [1] 5 💬 💬 |
132 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 [1] 206 💬 💬 |
133 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 [1] 5 💬 💬 |
134 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
135 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Diflunisal Diflunisal 💬 |
Diflunisal | 028 [1] 28 💬 💬 |
136 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Etodolac Etodolac 💬 |
Etodolac | 046 [1] 46 💬 💬 |
137 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Etoricoxib Etoricoxib 💬 |
Etoricoxib | 046 [2] 46, 271 💬 💬 |
138 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Lumiracoxib Lumiracoxib 💬 |
Lumiracoxib | 046 [1] 46 💬 💬 |
139 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Meloxicam Meloxicam 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 💬 |
140 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Nimesulide Nimesulide 💬 |
Nimesulide | 046 [1] 46 💬 💬 |
141 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Parecoxib Parecoxib 💬 |
Parecoxib | 046 [2] 46, 271 💬 💬 |
142 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Rofecoxib Rofecoxib 💬 |
Rofecoxib | 046 [1] 46 💬 💬 |
143 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Valdecoxib Valdecoxib 💬 |
Valdecoxib | 046 [1] 46 💬 💬 |
144 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM1 [1] RRM1 💬 |
Cladribine Cladribine 💬 |
Cladribine | 011 [3] 11, 13, 94 💬 💬 |
145 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM1 [1] RRM1 💬 |
Clofarabine Clofarabine 💬 |
Clofarabine | 019 [5] 19, 20, 60, 234, 326 💬 💬 |
146 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM1 [1] RRM1 💬 |
Fludarabine Fludarabine 💬 |
Fludarabine | 011 [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 💬 |
147 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
148 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
SMPD1 [1] SMPD1 💬 |
Olipudase alfa Olipudase alfa 💬 |
Olipudase alfa | 019 [1] 19 💬 💬 |
149 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
SRD5A1 [2] SRD5A1, SRD5A2 💬 |
Dutasteride Dutasteride 💬 |
Dutasteride | 001 [2] 1 , 2 💬 💬 |
150 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
SRD5A2 [1] SRD5A2 💬 |
Finasteride Finasteride 💬 |
Finasteride | 006 [1] 6 💬 💬 |
151 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
TPH1 [2] TPH1, TPH2 💬 |
Telotristat Telotristat 💬 |
Telotristat | 097 [1] 97 💬 💬 |
152 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
TPO [1] TPO 💬 |
Methimazole Methimazole 💬 |
Methimazole | 050 [1] 50 💬 💬 |
153 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
TYMS [1] TYMS 💬 |
Tegafur Tegafur 💬 |
Tegafur | 046 [1] 46 💬 💬 |
154 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
UGCG [1] UGCG 💬 |
Eliglustat Eliglustat 💬 |
Eliglustat | 019 [1] 19 💬 💬 |
155 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
UGCG [1] UGCG 💬 |
Lucerastat Lucerastat 💬 |
Lucerastat | 019 [1] 19 💬 💬 |
156 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
UGCG [1] UGCG 💬 |
Miglustat Miglustat 💬 |
Miglustat | 019 [3] 19, 256, 299 💬 💬 |
157 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
UGCG [1] UGCG 💬 |
Venglustat Venglustat 💬 |
Venglustat | 006 [3] 6 , 19, 67 💬 💬 |
158 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
VKORC1 [1] VKORC1 💬 |
Phenindione Phenindione 💬 |
Phenindione | 065 [1] 65 💬 💬 |
159 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
160 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
XDH [1] XDH 💬 |
Febuxostat Febuxostat 💬 |
Febuxostat | 002 [3] 2 , 6 , 13 💬 💬 |