Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Platinum drug resistance 💬

[1] BCL2 💬

Venetoclax 💬

[1] 28 💬

2

Platinum drug resistance 💬

[1] CASP9 💬

[6] 19, 60, 65, 284, 285, 326 💬

3

Platinum drug resistance 💬

[1] ERBB2 💬

[3] 34, 74, 75 💬

4

Platinum drug resistance 💬

[1] ERBB2 💬

[1] 34 💬

5

Platinum drug resistance 💬

[1] ERBB2 💬

Tesevatinib 💬

[1] 67 💬

6

Platinum drug resistance 💬

[1] MAP3K5 💬

Selonsertib 💬

[1] 86 💬

7

Platinum drug resistance 💬

[1] PIK3CA 💬

[1] 138 💬

8

Platinum drug resistance 💬

[3] PIK3CA, PIK3CB, PIK3CD 💬

Name	Full Name
PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

Leniolisib 💬

[2] 53, 65 💬

9

Platinum drug resistance 💬

[1] PIK3CD 💬

Parsaclisib 💬

[3] 35, 53, 61 💬

10

Platinum drug resistance 💬

[2] TOP2A, TOP2B 💬

Daunorubicin 💬

[1] 65 💬

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