Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [1] ABL1 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
2 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [1] ABL1 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
3 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬 |
Bosutinib Bosutinib 💬 |
Bosutinib | 002 [2] 2 , 67 💬 💬 |
4 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
5 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
6 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
ABL1 [2] ABL1, SRC 💬 |
Saracatinib Saracatinib 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 💬 |
7 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
8 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
BRAF [2] BRAF, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
9 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
10 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
11 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
12 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
13 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
14 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [2] EGFR, ERBB2 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
15 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
EGFR [3] EGFR, ERBB2, ERBB4 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
16 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
17 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
18 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
19 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
20 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
21 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Everolimus Everolimus 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬 |
22 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
23 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR [1] MTOR 💬 |
Temsirolimus Temsirolimus 💬 |
Temsirolimus | 013 [1] 13 💬 💬 |
24 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
25 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
26 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |
27 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
PRKCB [1] PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 [1] 168 💬 💬 |