Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

VEGF signaling pathway 💬

[1] CASP9 💬

[6] 19, 60, 65, 284, 285, 326 💬

2

VEGF signaling pathway 💬

[1] KDR 💬

[1] 34 💬

3

VEGF signaling pathway 💬

[1] KDR 💬

Cabozantinib 💬

[1] 34 💬

4

VEGF signaling pathway 💬

[1] KDR 💬

[1] 34 💬

5

VEGF signaling pathway 💬

[1] KDR 💬

Nintedanib 💬

[5] 51, 85, 89, 227, 228 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
89	Lymphangioleiomyomatosis;LAM;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

6

VEGF signaling pathway 💬

[1] KDR 💬

[2] 28, 34 💬

7

VEGF signaling pathway 💬

[1] KDR 💬

Tesevatinib 💬

[1] 67 💬

8

VEGF signaling pathway 💬

[2] KDR, RAF1 💬

[2] 34, 86 💬

9

VEGF signaling pathway 💬

[2] MAP2K1, MAP2K2 💬

Binimetinib 💬

[1] 34 💬

10

VEGF signaling pathway 💬

[2] MAP2K1, MAP2K2 💬

Cobimetinib 💬

[1] 280 💬

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