Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Renin secretion 💬

[1] ACE 💬

Benazepril 💬

[4] 49, 57, 218, 224 💬

2

Renin secretion 💬

[1] ACE 💬

[8] 6 , 17, 46, 86, 96, 97, 107, 271 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
17	Multiple system atrophy;MSA-C;MSA-P;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
86	Pulmonary arterial hypertension;PAH;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

3

Renin secretion 💬

[1] ACE 💬

Cilazapril 💬

[1] 66 💬

4

Renin secretion 💬

[1] ACE 💬

Cilazapril 💬

[1] 66 💬

5

Renin secretion 💬

[1] ACE 💬

[6] 19, 46, 66, 113, 210, 222 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
113	Muscular dystrophy;
210	Single Ventricle;SV;Single ventricle heart defect;Univentricular heart;UVH;Single ventricular circulation syndrome;
222	Primary nephrotic syndrome;

6

Renin secretion 💬

[1] ACE 💬

[1] 67 💬

7

Renin secretion 💬

[1] ACE 💬

Lisinopril 💬

[7] 19, 46, 49, 66, 67, 113, 222 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
113	Muscular dystrophy;
222	Primary nephrotic syndrome;

8

Renin secretion 💬

[1] ACE 💬

Lisinopril 💬

[7] 19, 46, 49, 66, 67, 113, 222 💬

Disease ID	Name
19	Lysosomal storage disease;Lysosomal disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
113	Muscular dystrophy;
222	Primary nephrotic syndrome;

9

Renin secretion 💬

[1] ACE 💬

[1] 93 💬

10

Renin secretion 💬

[1] ACE 💬

Perindopril 💬

[4] 58, 113, 167, 222 💬

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