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No.	KEGG PATHWAY	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	Angiotensin II 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬 💬
2	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	Angiotensin II 💬	Angiotensin II	[7] 17, 19, 46, 66, 86, 222, 224 💬 💬
3	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	Candesartan 💬	Candesartan	[2] 58, 67 💬 💬
4	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	Candesartan cilexetil 💬	Candesartan cilexetil	[1] 67 💬 💬
5	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	Irbesartan 💬	Irbesartan	[4] 66, 167, 168, 222 💬 💬
6	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	Losartan 💬	Losartan	[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 💬
7	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	Sparsentan 💬	Sparsentan	[3] 66, 218, 222 💬 💬
8	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	Telmisartan 💬	Telmisartan	[2] 66, 67 💬 💬
9	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	Valsartan 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬 💬
10	Aldosterone synthesis and secretion 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	Digitoxin 💬	Digitoxin	[1] 299 💬 💬
11	Aldosterone synthesis and secretion 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	Digoxin 💬	Digoxin	[3] 8 , 46, 210 💬 💬
12	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Amlodipine 💬	Amlodipine	[4] 13, 51, 67, 298 💬 💬
13	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Cilnidipine 💬	Cilnidipine	[1] 67 💬 💬
14	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Diltiazem 💬	Diltiazem	[3] 51, 58, 86 💬 💬
15	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Isradipine 💬	Isradipine	[1] 6 💬 💬
16	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Nicardipine 💬	Nicardipine	[2] 70, 86 💬 💬
17	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Nifedipine 💬	Nifedipine	[2] 50, 81 💬 💬
18	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Nilvadipine 💬	Nilvadipine	[1] 90 💬 💬
19	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Perhexiline 💬	Perhexiline	[2] 58, 272 💬 💬
20	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Propiverine 💬	Propiverine	[1] 226 💬 💬
21	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Topiramate 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬 💬
22	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	Verapamil 💬	Verapamil	[4] 58, 96, 140, 167 💬 💬
23	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	Flunarizine 💬	Flunarizine	[1] 149 💬 💬
24	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	Valproic acid 💬	Valproic acid	[14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬
25	Aldosterone synthesis and secretion 💬	[3] CACNA1G, CACNA1H, CACNA1I 💬	Zonisamide 💬	Zonisamide	[1] 6 💬 💬
26	Aldosterone synthesis and secretion 💬	[1] CYP11A1 💬	Levoketoconazole 💬	Levoketoconazole	[1] 75 💬 💬
27	Aldosterone synthesis and secretion 💬	[1] CYP11B2 💬	Osilodrostat 💬	Osilodrostat	[1] 75 💬 💬
28	Aldosterone synthesis and secretion 💬	[1] KCNJ5 💬	Amiodarone 💬	Amiodarone	[2] 28, 127 💬 💬
29	Aldosterone synthesis and secretion 💬	[1] MC2R 💬	Corticotropin 💬	Corticotropin	[12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬
30	Aldosterone synthesis and secretion 💬	[1] MC2R 💬	Cosyntropin 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬 💬
31	Aldosterone synthesis and secretion 💬	[1] NPR1 💬	Erythrityl tetranitrate 💬	Erythrityl tetranitrate	[1] 46 💬 💬
32	Aldosterone synthesis and secretion 💬	[1] NPR1 💬	Nesiritide 💬	Nesiritide	[2] 46, 58 💬 💬
33	Aldosterone synthesis and secretion 💬	[1] PDE2A 💬	Aminophylline 💬	Aminophylline	[1] 63 💬 💬
34	Aldosterone synthesis and secretion 💬	[1] PDE2A 💬	Bucladesine 💬	Bucladesine	[1] 246 💬 💬
35	Aldosterone synthesis and secretion 💬	[1] PDE2A 💬	Caffeine 💬	Caffeine	[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬
36	Aldosterone synthesis and secretion 💬	[1] PDE2A 💬	Caffeine hydrate 💬	Caffeine	[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬
37	Aldosterone synthesis and secretion 💬	[1] PDE2A 💬	Flavoxate 💬	Flavoxate	[1] 226 💬 💬
38	Aldosterone synthesis and secretion 💬	[1] PDE2A 💬	Theophylline 💬	Theophylline	[2] 236, 299 💬 💬
39	Aldosterone synthesis and secretion 💬	[1] PDE2A 💬	Theophylline 💬	Theophylline	[2] 236, 299 💬 💬
40	Aldosterone synthesis and secretion 💬	[1] PRKCB 💬	Enzastaurin 💬	Enzastaurin	[1] 168 💬 💬
41	Aldosterone synthesis and secretion 💬	[1] PRKCE 💬	Sotrastaurin 💬	Sotrastaurin	[1] 97 💬 💬