Target Gene/Pathway Pathway / Gene

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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Viral carcinogenesis 💬

[1] C3 💬

Pegcetacoplan 💬

[4] 2 , 61, 62, 222 💬

2

Viral carcinogenesis 💬

[1] CCR4 💬

Mogamulizumab 💬

[1] 26 💬

3

Viral carcinogenesis 💬

[1] CCR5 💬

Cenicriviroc 💬

[1] 94 💬

4

Viral carcinogenesis 💬

[1] CCR5 💬

[2] 46, 84 💬

5

Viral carcinogenesis 💬

[2] CDK4, CDK6 💬

Abemaciclib 💬

[1] 34 💬

6

Viral carcinogenesis 💬

[11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬

Name	Full Name
HDAC1	histone deacetylase 1
HDAC10	histone deacetylase 10
HDAC11	histone deacetylase 11
HDAC2	histone deacetylase 2
HDAC3	histone deacetylase 3
HDAC4	histone deacetylase 4
HDAC5	histone deacetylase 5
HDAC6	histone deacetylase 6
HDAC7	histone deacetylase 7
HDAC8	histone deacetylase 8
HDAC9	histone deacetylase 9

Vorinostat 💬

[2] 75, 96 💬

7

Viral carcinogenesis 💬

[1] JAK1 💬

Abrocitinib 💬

[1] 84 💬

8

Viral carcinogenesis 💬

[1] JAK1 💬

Baricitinib 💬

[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
41	Giant cell arteritis;Temporal arteritis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
107	Juvenile idiopathic arthritis;JIA;
162	Pemphigoid;
265	Lipodystrophy;
269	Pyogenic arthritis;Pyoderma gangrenosum;Acne syndrome;PAPA syndrome;
325	Hereditary autoinflammatory syndrome;

9

Viral carcinogenesis 💬

[1] JAK1 💬

Filgotinib 💬

[6] 46, 53, 96, 97, 222, 271 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
222	Primary nephrotic syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;

10

Viral carcinogenesis 💬

[1] JAK1 💬

Itacitinib 💬

[4] 46, 51, 97, 228 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
97	Ulcerative colitis;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

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