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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
110-mg dose of E5501 2G tablet----[1] 63
210-mg dose of E5501 cyclodextrin oral solution----[1] 63
310-mg dose of E5501 lipid-based oral----[1] 63
410-mg dose of E5501-P21% powder----[1] 63
5Acetominofene----[2] 11, 63
6Acetominophen----[1] 63
7Acetylcysteine[1] Acetylcysteine[1] D00221 --[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
8AKR-501, YM-477----[1] 63
9ALEMTUZUMAB[1] Alemtuzumab[1] D02802 [1] CD52 💬-[17] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284
10Alemtuzumab, Rituximab[2] Alemtuzumab,
Rituximab
[2] D02802 ,
D02994
[2] CD52,
MS4A1 💬
-[1] 63
11All-Trans Retinoid Acid(ATRA)[1] Tretinoin[1] D00094 [3] PML,
RARA,
RARB 💬
[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[1] 63
12AMG 531----[1] 63
13AMG531----[2] 60, 63
14Aminophylline[1] Aminophylline[1] D00227 [18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬
[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 63
15Amoxicillin[1] Amoxicillin[2] D00229 ,
D07452
--[7] 6, 46, 63, 96, 97, 222, 299
16Amoxicillin hydrate[1] Amoxicillin[2] D00229 ,
D07452
--[1] 63
17Amoxycillin[1] Amoxicillin[2] D00229 ,
D07452
--[1] 63
18Anti-CD40L[1] Toralizumab[1] D06193 [1] CD40LG 💬[14] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬[1] 63
19Anti-CD40LdAb----[1] 63
20Anti-D----[1] 63
21ARGX-113----[5] 11, 14, 35, 53, 63
22Atorvastatin[1] Atorvastatin[1] D07474 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
23Atorvastatin 10mg[1] Atorvastatin[1] D07474 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 63
24Atorvastatin 20mg[1] Atorvastatin[1] D07474 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 63
25Atorvastatin 40 Mg Oral Tablet + N-acetylcysteine 400 mg Oral tablet[2] Acetylcysteine,
Atorvastatin
[2] D00221 ,
D07474
[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 63
26ATRA[1] Tretinoin[1] D00094 [3] PML,
RARA,
RARB 💬
[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[2] 63, 94
27Avatrombopag[1] Avatrombopag[1] D10306 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[2] 60, 63
28Avatrombopag (proposed)[1] Avatrombopag[1] D10306 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 63
29AVATROMBOPAG MALEATE[1] Avatrombopag[1] D10306 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 63
30Avatrombopag tablets[1] Avatrombopag[1] D10306 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 63
31Azathioprine[1] Azathioprine[1] D00238 --[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
32BELIMUMAB[1] Belimumab[1] D03068 [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300
33Blinded (Avatrombopoag tablets)----[1] 63
34Blisibimod[1] Blisibimod[1] D10311 --[5] 43, 44, 49, 63, 66
35BMS-986004----[1] 63
36BMS-986004 1500 mg IV----[1] 63
37BMS-986004 225 mg IV----[1] 63
38BMS-986004 675 mg IV----[1] 63
39BMS-986004 75 mg IV----[1] 63
40BORTEZOMIB[1] Bortezomib[1] D03150 [1] PSMB5 💬[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331
41BT595----[2] 63, 65
42Caffeic acid tablets----[1] 63
43CD----[8] 6, 13, 46, 51, 63, 96, 97, 265
44Clarithromycin[1] Clarithromycin[1] D00276 --[8] 6, 63, 84, 96, 97, 222, 228, 299
45Combination of Rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 63
46Combination of Rituximab with subcutaneous belimumab[2] Belimumab,
Rituximab
[2] D02994 ,
D03068
[2] MS4A1,
TNFSF13B 💬
[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 63
47Conventional----[1] 63
48Corticosteroids----[12] 41, 46, 49, 63, 64, 97, 107, 113, 164, 220, 296, 300
49Corticosteroids (Aprednislon)----[1] 63
50CsA----[8] 19, 49, 50, 53, 60, 63, 222, 228
51Cyclosporin[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[17] 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326
52Cyclosporin A[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[11] 46, 49, 53, 56, 60, 62, 63, 93, 95, 113, 164
53Cyclosporine[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
54Danazol[1] Danazol[1] D00289 [3] AR,
ESR1,
PGR 💬
[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 60, 63, 64, 65, 285
55Daratumumab[1] Daratumumab[1] D10777 [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[5] 13, 28, 48, 49, 63
56Daratumumab Injection[1] Daratumumab[1] D10777 [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[3] 28, 49, 63
57Darzalex[1] Daratumumab[1] D10777 [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[3] 28, 49, 63
58Decitabine[1] Decitabine[1] D03665 [3] DNMT1,
DNMT3A,
DNMT3B 💬
[3] Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer 💬[2] 60, 63
59Dexamethasone[1] Dexamethasone[1] D00292 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
60Dexamethasone (1 cycle)[1] Dexamethasone[1] D00292 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 63
61Dexamethasone (4 cycles)[1] Dexamethasone[1] D00292 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 63
62Dexamethasone Abcur[1] Dexamethasone[1] D00292 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 63
63Dexamethasone and Rituximab[2] Dexamethasone,
Rituximab
[2] D00292 ,
D02994
[2] MS4A1,
NR3C1 💬
[2] Hematopoietic cell lineage, Neuroactive ligand-receptor interaction 💬[1] 63
64DIACEREIN[1] Diacerein[1] D07270 --[3] 36, 46, 63
65Diammonium glycyrrhizinate enteric-coated capsule----[1] 63
66Difenidramina----[2] 11, 63
67DIFENIDRAMINA CLORIDRATO----[3] 11, 19, 63
68Doptelet[1] Avatrombopag[1] D10306 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 63
69Doptelet 20 mg film-coated tablets[1] Avatrombopag[1] D10306 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 63
70Doxil----[1] 63
71Dyphenhydramine hydrochloride----[1] 63
72E5501----[1] 63
73E5501 40 mg 2 x 20-mg tablets, orally, fasted----[1] 63
74E5501 40 mg 2 x 20-mg tablets, orally, with food----[1] 63
75E5501 40mg 2 x 20-mg tablets, orally, fasted----[1] 63
76Efgartigimod----[4] 11, 35, 53, 63
77EFGARTIGIMOD ALFA[1] Efgartigimod alfa[1] D11876 [1] FCGRT 💬-[6] 11, 14, 35, 53, 63, 162
78Efgartigimod alpha----[1] 63
79Efgartigimod PH20 SC----[5] 11, 14, 35, 63, 162
80ELTROMBOPAG[1] Eltrombopag---[5] 60, 63, 65, 284, 285
81Eltrombopag (Revolade)[1] Eltrombopag---[1] 63
82Eltrombopag (Revolade®)[1] Eltrombopag---[1] 63
83Eltrombopag combining rituximab[2] Eltrombopag,
Rituximab
[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 63
84ELTROMBOPAG OLAMINE[1] Eltrombopag---[2] 60, 63
85Eltrombopag olamine (SB-497115-GR)[1] Eltrombopag---[1] 63
86Eltrombopag olamine, Revolade, Promacta[1] Eltrombopag---[1] 63
87Eltrombopag oral tablets[1] Eltrombopag---[1] 63
88Eltrombopag plus diacerein[2] Diacerein,
Eltrombopag
[1] D07270 --[1] 63
89Gammaplex----[2] 63, 65
90Gammaplex, intravenous immunoglobulin----[1] 63
91Global DNA methylation will be quantified in the DNA samples by colorimetry----[1] 63
92Glycyrrhetinic Acid----[1] 63
93GMA161----[1] 63
94GNR-069----[1] 63
95Gold[1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
96HBM9161 Dose A----[1] 63
97HBM9161 Dose B----[1] 63
98Herombopag----[2] 60, 63
99Hetrombopag[1] Hetrombopag---[2] 60, 63
100Hetrombopag Olamine[1] Hetrombopag---[2] 60, 63
101High dose Dexamethasone pulses[1] Dexamethasone[1] D00292 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 63
102HMPL-523----[2] 46, 63
103Huaiqihuang Granule----[2] 63, 222
104Human Immunoglobulin----[2] 63, 65
105HUMAN IMMUNOGLOBULIN G[1] Human immunoglobulin G---[4] 14, 50, 63, 65
106Human normal immunoglobulin[1] Human immunoglobulin G---[9] 11, 13, 14, 43, 45, 50, 51, 63, 65
107HUMAN NORMAL IMMUNOGLOBULIN (IV)[1] Human immunoglobulin G---[4] 11, 14, 63, 65
108HUMAN NORMAL IMMUNOGLOBULIN FOR INTRAVENOUS USE[1] Human immunoglobulin G---[2] 63, 65
109HUMAN NORMAL IMMUNOGLOBULIN FOR INTRVENOUS USE[1] Human immunoglobulin G---[1] 63
110Human normal immunoglobulin G (IgG > 98% purity)[1] Human immunoglobulin G---[3] 14, 63, 65
111HUMAX-CD38----[2] 28, 63
112Hydroxychloroquine[1] Hydroxychloroquine[1] D08050 --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
113I10E----[3] 14, 63, 65
114Ianalumab[1] Ianalumab[1] D12151 [1] TNFRSF13C 💬[5] Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬[7] 35, 46, 49, 53, 61, 63, 95
115Ig VENA----[2] 50, 63
116Ig VENA 100 ml vial----[1] 63
117Ig VENA 50 g/l solution for infusion 100 ml vial + infusion set----[2] 63, 65
118IgG Next Generation----[2] 63, 65
119IGIV3I Grifols 10%----[1] 63
120IgNextGen 10%----[1] 63
121Immune Globulin Intravenous (Human), 10% Triple Virally Reduced Solution----[1] 63
122Immunglobulin----[1] 63
123Immunoglobulin----[3] 13, 14, 63
124IMMUNOGLOBULIN G----[8] 2, 11, 13, 14, 49, 50, 63, 65
125Inactivated Trivalent Influenza vaccine----[1] 63
126INTERLEUKIN 2----[9] 46, 49, 51, 56, 63, 95, 96, 97, 271
127Intravenous immunoglobulin (IVIG), 10% solution for infusion----[1] 63
128IVIG-L----[1] 63
129L01FC01----[1] 63
130Lansoprazole[1] Lansoprazole[1] D00355 [2] ATP4A,
ATP4B 💬
[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299
131Lansoprazole, clarithromycin, amoxycillin[3] Amoxicillin,
Clarithromycin,
Lansoprazole
[4] D00229 ,
D00276 ,
D00355 ,
D07452
[2] ATP4A,
ATP4B 💬
[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 63
132LIV-GAMMA SN Inj.----[1] 63
133LIV-GAMMA SN Inj.10%----[1] 63
134MabThera[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[22] 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271
135Medical Standard of Care for ITP----[1] 63
136Methylprednisolone[1] Methylprednisolone[1] D00407 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
137METILPREDNISOLONE----[6] 11, 13, 53, 56, 63, 300
138METRONIDAZOLE[1] Metronidazole[1] D00409 --[7] 46, 51, 63, 94, 96, 97, 291
139Mezagitamab[1] Mezagitamab[1] D11945 [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[2] 63, 66
140Mg----[5] 6, 13, 51, 63, 111
141Montelukast[1] Montelukast[1] D08229 [1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228
142Nanogam----[1] 63
143NewGam----[3] 14, 63, 65
144NPLATE[1] Romiplostim[1] D08990 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 63
145NPLATE 500 microgramos polvo para solución inyectable[1] Romiplostim[1] D08990 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 63
146Null----[16] 6, 13, 15, 28, 37, 46, 49, 51, 63, 86, 90, 96, 97, 107, 145, 271
147Octagam 10%----[3] 50, 63, 65
148Octagam® 10%----[1] 63
149Open Label (Avatrombopag tablets)[1] Avatrombopag[1] D10306 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 63
150Orelabrutinib[1] Orelabrutinib[1] D12160 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[4] 13, 49, 61, 63
151Orelabrutinib( higher dose)[1] Orelabrutinib[1] D12160 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 63
152Orelabrutinib( lower dose)[1] Orelabrutinib[1] D12160 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 63
153Palmitate[1] Palmitic Acid[1] D05341 --[1] 63
154PARACETAMOLO----[9] 2, 11, 14, 19, 28, 53, 61, 63, 300
155PF-06755347 intravenous healthy participant----[1] 63
156PF-06755347 subcutaneous healthy participant----[1] 63
157PF-06755347 subcutaneous ITP----[1] 63
158PF-06835375----[3] 46, 49, 63
159PG2----[1] 63
160Placebo----[28] 3, 5, 6, 11, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276
161Povetacicept----[3] 61, 63, 222
162PREDNISOLONE[1] Prednisolone[1] D00472 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
163Prednisone[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
164Privigen®[1] Human immunoglobulin G---[3] 14, 63, 65
165Promacta[1] Eltrombopag---[2] 63, 65
166Proteína recombinante estimulante de la megacariopoyesis----[1] 63
167PRTX-100 (Staphylococcal protein A)[1] Bevifimod---[1] 63
168QL0911----[1] 63
169R788----[2] 46, 63
170Recombinant Human Thrombopoietin[2] Recombinant Human Thrombopoietin,
Thrombopoietin
---[1] 63
171Recombinant human thrombopoietin (rh-TPO)[2] Recombinant Human Thrombopoietin,
Thrombopoietin
---[1] 63
172Recombinant Human Thrombopoietin (rhTPO)[2] Recombinant Human Thrombopoietin,
Thrombopoietin
---[1] 63
173Relovade----[1] 63
174REVOLADE[1] Eltrombopag---[2] 60, 63
175Revolade 25 mg film-coated tablets[1] Eltrombopag---[1] 63
176Revolade 50 mg film-coated tablets[1] Eltrombopag---[1] 63
177REVOLADE, PROMACTA[1] Eltrombopag---[1] 63
178RhTPO[1] Recombinant Human Thrombopoietin---[2] 60, 63
179RhTPO in combination with Rituximab[2] Recombinant Human Thrombopoietin,
Rituximab
[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 63
180RITUXIMAB[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
181Rituximab [MabThera/Rituxan][1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[2] 46, 63
182Romiplostim[1] Romiplostim[1] D08990 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[4] 60, 63, 64, 65
183Romiplostim plus dexamethasone[2] Dexamethasone,
Romiplostim
[2] D00292 ,
D08990
[2] MPL,
NR3C1 💬
[3] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 63
184Romiplostin----[1] 63
185ROZANOLIXIZUMAB[1] Rozanolixizumab[1] D12182 [1] FCGRT 💬-[3] 11, 14, 63
186SB-497115----[1] 63
187SB-497115-GR----[1] 63
188SB-497115-GR 12.5mg----[1] 63
189SB-497115-GR 25mg----[1] 63
190SB-497115-GR 50 mg----[1] 63
191SB497115----[2] 60, 63
192Sirolimus[1] Sirolimus[1] D00753 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[35] 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 98, 137, 157, 158, 192, 222, 277, 278, 279, 280, 281, 283, 300, 331
193SM101----[3] 49, 63, 66
194SM101 20mg/mL----[1] 63
195SM101 5mg/mL----[1] 63
196Standard of Care----[8] 6, 13, 49, 51, 63, 64, 79, 171
197Standard therapy (without eltrombopag): HD-DXM[1] Eltrombopag---[1] 63
198STAPHYLOCOCCAL PROTEIN A[1] Bevifimod---[1] 63
199Steroids----[7] 46, 50, 51, 63, 66, 96, 97
200TAK-079----[3] 11, 49, 63
201Takecab tablets + amoxicillin + clarithromycin (first-line eradication) Takecab tablets + amoxicillin + metronidazole (second-line eradication)[3] Amoxicillin,
Clarithromycin,
Metronidazole
[4] D00229 ,
D00276 ,
D00409 ,
D07452
--[1] 63
202Thrombopoietin[1] Thrombopoietin---[3] 47, 60, 63
203TPO----[1] 63
204TPO-RA----[1] 63
205TPO-RAs----[1] 63
206TPO-RAs combining anti-CD 20 monoclonal antibody----[1] 63
207Triple therapy----[2] 50, 63
208TYSABRI[1] Natalizumab[1] D06886 [1] ITGA4 💬[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[3] 13, 25, 63
209UCB7665----[3] 11, 14, 63
210VAY736----[9] 13, 35, 46, 49, 53, 61, 63, 85, 95
211Vonoprazan[1] Vonoprazan[1] D11784 [2] ATP4A,
ATP4B 💬
[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 63, 98
212Water[1] Water[1] D00001 --[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299
213Zanubrutinib[1] Zanubrutinib[1] D11422 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[5] 13, 63, 222, 300, 331