Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	ATP1A1	[1] Thyroid hormone synthesis	D00297	Digitoxin	[1] 299
2	ATP1A1	[1] Thyroid hormone synthesis	D00298	Digoxin	[3] 8, 46, 210
3	ATP1A2	[1] Thyroid hormone synthesis	D00297	Digitoxin	[1] 299
4	ATP1A2	[1] Thyroid hormone synthesis	D00298	Digoxin	[3] 8, 46, 210
5	ATP1A3	[1] Thyroid hormone synthesis	D00297	Digitoxin	[1] 299
6	ATP1A3	[1] Thyroid hormone synthesis	D00298	Digoxin	[3] 8, 46, 210
7	ATP1A4	[1] Thyroid hormone synthesis	D00297	Digitoxin	[1] 299
8	ATP1A4	[1] Thyroid hormone synthesis	D00298	Digoxin	[3] 8, 46, 210
9	PRKCB	[4] Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Thyroid hormo ...	D11935	Enzastaurin	[1] 168
10	TPO	[2] Tyrosine metabolism, Thyroid hormone synthesis	D00401	Methimazole	[1] 50

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