Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[3] CSF1R, FLT3, KIT 💬	D08552 💬	Sunitinib	[2] 28, 34 💬
2	Acute myeloid leukemia 💬	[1] KIT 💬	D08066 💬	Imatinib	[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
3	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
4	Adipocytokine signaling pathway 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
5	Adipocytokine signaling pathway 💬	[1] TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
6	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
7	Adrenergic signaling in cardiomyocytes 💬	[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNQ1, SCN5A 💬	D02910 💬	Amiodarone	[2] 28, 127 💬
8	Adrenergic signaling in cardiomyocytes 💬	[1] BCL2 💬	D10679 💬	Venetoclax	[1] 28 💬
9	African trypanosomiasis 💬	[1] IL6 💬	D09669 💬	Siltuximab	[2] 28, 331 💬
10	African trypanosomiasis 💬	[2] IL6, TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬

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