Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Longevity regulating pathway 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
2 Longevity regulating pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
3 Longevity regulating pathway 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
4 Longevity regulating pathway 💬
 [1] INSR 💬 D04539 💬 Insulin detemir [1] 299 💬
5 Longevity regulating pathway 💬
 [1] INSR 💬 D03250 💬 Insulin glargine [1] 299 💬
6 Longevity regulating pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
7 Longevity regulating pathway 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
8 Longevity regulating pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
9 Longevity regulating pathway 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
10 Longevity regulating pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
11 Longevity regulating pathway 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
12 Longevity regulating pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
13 Longevity regulating pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
14 Longevity regulating pathway 💬
 [1] PPARG 💬 D12242 💬 Bocidelpar [1] 113 💬
15 Longevity regulating pathway 💬
 [1] PPARG 💬 D11603 💬 Leriglitazone [1] 20 💬
16 Longevity regulating pathway 💬
 [1] PPARG 💬 D08378 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
17 Longevity regulating pathway 💬
 [1] PPARG 💬 D08491 💬 Rosiglitazone [5] 46, 75, 97, 222, 265 💬
18 Longevity regulating pathway 💬
 [1] PPARG 💬 D11256 💬 Seladelpar [2] 93, 94 💬
19 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
20 Longevity regulating pathway 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
21 Longevity regulating pathway - multiple species 💬
 [2] HDAC1, HDAC2 💬 D06320 💬 Vorinostat [2] 75, 96 💬
22 Longevity regulating pathway - multiple species 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
23 Longevity regulating pathway - multiple species 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
24 Longevity regulating pathway - multiple species 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
25 Longevity regulating pathway - multiple species 💬
 [1] INSR 💬 D04539 💬 Insulin detemir [1] 299 💬
26 Longevity regulating pathway - multiple species 💬
 [1] INSR 💬 D03250 💬 Insulin glargine [1] 299 💬
27 Longevity regulating pathway - multiple species 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
28 Longevity regulating pathway - multiple species 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
29 Longevity regulating pathway - multiple species 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
30 Longevity regulating pathway - multiple species 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
31 Longevity regulating pathway - multiple species 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
32 Longevity regulating pathway - multiple species 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
33 Longevity regulating pathway - multiple species 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
34 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
35 Longevity regulating pathway - multiple species 💬
 [1] SOD1 💬 D11811 💬 Tofersen [1]  2  💬

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