Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 EGFR [7] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D01977 Gefitinib [1] 75
2 EGFR [7] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D03455 Cetuximab [5] 34, 51, 86, 89, 331
3 EGFR [7] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D04023 Erlotinib [1] 94
4 EGFR [7] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D04024 Lapatinib [3] 34, 74, 75
5 EGFR [7] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D07907 Erlotinib [1] 94
6 EGFR [7] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D08108 Lapatinib [3] 34, 74, 75
7 EGFR [7] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D11251 Icotinib [1] 34
8 EGFR [7] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Proteoglycans in cancer, Prostate cancer D11772 Tesevatinib [1] 67
9 ERBB2 [3] Tight junction, Proteoglycans in cancer, Prostate cancer D04024 Lapatinib [3] 34, 74, 75
10 ERBB2 [3] Tight junction, Proteoglycans in cancer, Prostate cancer D08108 Lapatinib [3] 34, 74, 75
11 ERBB2 [3] Tight junction, Proteoglycans in cancer, Prostate cancer D11772 Tesevatinib [1] 67
12 FGFR1 [7] Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Proteoglycans in cancer, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
13 FGFR1 [7] Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Proteoglycans in cancer, Prostate cancer D11589 Infigratinib [1] 276
14 FGFR2 [5] Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Prostate cancer D05338 Palifermin [5] 13, 36, 38, 39, 65
15 FGFR2 [5] Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
16 FGFR2 [5] Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Prostate cancer D11589 Infigratinib [1] 276
17 MTOR [8] Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer, Prostate cancer D00753 Sirolimus [41] 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
18 MTOR [8] Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer, Prostate cancer D02714 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277
19 MTOR [8] Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Proteoglycans in cancer, Prostate cancer D06068 Temsirolimus [4] 13, 34, 89, 331
20 IGF1R [6] Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D03297 Mecasermin [6] 65, 78, 96, 168, 265, 299
21 IGF1R [6] Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D04870 Mecasermin [6] 65, 78, 96, 168, 265, 299
22 IGF1R [6] Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D09680 Teprotumumab [1] 51
23 IGF1R [6] Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D09925 Linsitinib [1] 232
24 AR [1] Prostate cancer D00075 Testosterone [9] 1, 2, 3, 13, 60, 76, 78, 113, 265
25 AR [1] Prostate cancer D00289 Danazol [5] 60, 63, 64, 65, 285
26 AR [1] Prostate cancer D00444 Stanozolol [1] 60
27 AR [1] Prostate cancer D00462 Oxandrolone [2] 211, 285
28 AR [1] Prostate cancer D00586 Flutamide [1] 81
29 AR [1] Prostate cancer D00955 Nandrolone decanoate [2] 60, 85
30 AR [1] Prostate cancer D00957 Testosterone [9] 1, 2, 3, 13, 60, 76, 78, 113, 265
31 AR [1] Prostate cancer D00958 Testosterone [9] 1, 2, 3, 13, 60, 76, 78, 113, 265
32 AR [1] Prostate cancer D00958 Testosterone enanthate [2] 13, 113
33 AR [1] Prostate cancer D00959 Testosterone [9] 1, 2, 3, 13, 60, 76, 78, 113, 265
34 AR [1] Prostate cancer D00959 Testosterone propionate [1] 113
35 AR [1] Prostate cancer D03338 Calusterone [3] 2, 46, 71
36 AR [1] Prostate cancer D06085 Testosterone [9] 1, 2, 3, 13, 60, 76, 78, 113, 265
37 AR [1] Prostate cancer D06087 Testosterone [9] 1, 2, 3, 13, 60, 76, 78, 113, 265
38 AR [1] Prostate cancer D06087 Testosterone undecanoate [2] 13, 60
39 AR [1] Prostate cancer D08250 Nandrolone [2] 60, 85
40 AR [1] Prostate cancer D08409 Prasterone [6] 49, 53, 83, 86, 96, 113
41 AR [1] Prostate cancer D08573 Testosterone decanoate [1] 113
42 AR [1] Prostate cancer D08574 Testosterone phenylpropionate [1] 113
43 NFKB1 [18] Ras signaling pathway, Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer D01146 Iguratimod [4] 46, 51, 53, 271
44 PDGFRA [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D01441 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
45 PDGFRA [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D06402 Sunitinib [2] 28, 34
46 PDGFRA [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08066 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
47 PDGFRA [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08552 Sunitinib [2] 28, 34
48 PDGFRA [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08953 Nilotinib [5] 6, 8, 34, 51, 86
49 PDGFRA [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
50 PDGFRB [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D03658 Dasatinib [2] 51, 85
51 PDGFRB [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D06272 Sorafenib [2] 34, 86
52 PDGFRB [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D06402 Sunitinib [2] 28, 34
53 PDGFRB [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D06414 Dasatinib [2] 51, 85
54 PDGFRB [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08524 Sorafenib [2] 34, 86
55 PDGFRB [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08552 Sunitinib [2] 28, 34
56 PDGFRB [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D08953 Nilotinib [5] 6, 8, 34, 51, 86
57 PDGFRB [4] Ras signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton, Prostate cancer D10481 Nintedanib [5] 51, 85, 89, 227, 228
58 PIK3CA [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
59 PIK3CB [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
60 PIK3CD [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib [2] 53, 65
61 PIK3CD [22] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11437 Parsaclisib [3] 35, 53, 61
62 MAP2K1 [19] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D09666 Selumetinib [1] 34
63 MAP2K1 [19] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
64 MAP2K1 [19] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10405 Cobimetinib [1] 280
65 MAP2K1 [19] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10604 Binimetinib [1] 34
66 MAP2K2 [17] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D09666 Selumetinib [1] 34
67 MAP2K2 [17] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
68 MAP2K2 [17] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10405 Cobimetinib [1] 280
69 MAP2K2 [17] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10604 Binimetinib [1] 34
70 RAF1 [16] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer D06272 Sorafenib [2] 34, 86
71 RAF1 [16] Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer D08524 Sorafenib [2] 34, 86
72 BCL2 [8] Sphingolipid signaling pathway, Protein processing in endoplasmic reticulum, Shigellosis, Salmonella infection, Toxoplasmosis, Tuberculosis, Prostate cancer, Small cell lung cancer D10679 Venetoclax [1] 28
73 RELA [18] Ras signaling pathway, Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Prostate cancer, Small cell lung cancer D12181 Edasalonexent [1] 113
74 SRD5A2 [2] Steroid hormone biosynthesis, Prostate cancer D00321 Finasteride [1] 6
75 SRD5A2 [2] Steroid hormone biosynthesis, Prostate cancer D03820 Dutasteride [2] 1, 2
76 BRAF [8] Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D06272 Sorafenib [2] 34, 86
77 BRAF [8] Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D08524 Sorafenib [2] 34, 86
78 BRAF [8] Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10064 Dabrafenib [1] 34
79 IL1R2 [2] Transcriptional misregulation in cancer, Prostate cancer D02934 Anakinra [19] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
80 CASP9 [7] VEGF signaling pathway, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, Prostate cancer, Small cell lung cancer, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326