Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network for IgA production, Rheumatoid arthritis Belimumab 💬 Belimumab 13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
2 CSF3R 💬 5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer Filgrastim 💬 Filgrastim 35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
3 ADRA1D 💬 6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
4 ADRA1B 💬 6件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
5 ADRA1A 💬 7件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
6 ADRA2A 💬 2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
7 ADRA2B 💬 2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
8 ADRA2C 💬 2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
9 ADRB1 💬 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
10 ADRB1 💬 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy Propranolol 💬 Propranolol 6件: 6, 158, 167, 227, 278, 296 💬
11 ADRB2 💬 9件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
12 ADRB2 💬 9件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Propranolol 💬 Propranolol 6件: 6, 158, 167, 227, 278, 296 💬
13 ADRB3 💬 8件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
14 ADRB3 💬 8件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation Propranolol 💬 Propranolol 6件: 6, 158, 167, 227, 278, 296 💬
15 GABRA1 💬 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
16 GABRA2 💬 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
17 GABRA3 💬 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
18 GABRA4 💬 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
19 GABRA5 💬 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
20 GABRA6 💬 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
21 GABRB1 💬 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
22 GABRB2 💬 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
23 GABRB3 💬 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
24 GABRD 💬 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
25 GABRE 💬 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
26 GABRG1 💬 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
27 GABRG2 💬 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
28 GABRG3 💬 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
29 GABRP 💬 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
30 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone 22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
31 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone 46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
32 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone 42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
33 PPARA 💬 10件: PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hepatitis C, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy Bezafibrate 💬 Bezafibrate 7件: 20, 93, 94, 160, 296, 316, 324 💬
34 GABRQ 💬 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction Propofol 💬 Propofol 9件: 6, 21, 22, 34, 46, 70, 75, 98, 296 💬
35 PTGS2 💬 22件: Arachidonic acid metabolism, Metabolic pathways, NF-kappa B signaling pathway, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Meloxicam 💬 Meloxicam 4件: 46, 49, 271, 296 💬
36 SLC10A1 💬 2件: Bile secretion, Hepatitis B Maralixibat 💬 Maralixibat 3件: 296, 297, 338 💬
37 SLC10A2 💬 1件: Bile secretion Maralixibat 💬 Maralixibat 3件: 296, 297, 338 💬
38 SLC10A2 💬 1件: Bile secretion Odevixibat 💬 Odevixibat 3件: 296, 297, 338 💬
39 MS4A1 💬 1件: Hematopoietic cell lineage Rituximab 💬 Rituximab 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
40 KEAP1 💬 6件: Ubiquitin mediated proteolysis, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Dimethyl fumarate 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬
41 NR1H4 💬 1件: Bile secretion Ursodiol 💬 Ursodeoxycholic acid 14件: 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
42 NR1H4 💬 1件: Bile secretion Obeticholic acid 💬 Obeticholic acid 3件: 93, 265, 296 💬