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Target Gene/Pathway Pathway / Gene

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Showing 1 to 10 of 28 entries

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No.

KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[1] Cholesterol metabolism

Evinacumab 💬

[1] 79 💬

2

[4] Fat digestion and absorption, Vitamin digestion and absorption, Cholesterol metabolism, Lipid an ...

Mipomersen sodium 💬

[1] 79 💬

3

[1] Cholesterol metabolism

Torcetrapib 💬

[1] 79 💬

4

[1] Cholesterol metabolism

Anacetrapib 💬

[1] 79 💬

5

[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion

Pravastatin sodium 💬

[10] 13, 46, 49, 67, 79, 96, 164, 210, 265, 333 💬

Disease ID	Name
13	Multiple sclerosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
67	Polycystic kidney disease
79	Homozygous familial hypercholesterolemia
96	Crohn disease
164	Oculocutaneous albinism
210	Single Ventricle
265	Lipodystrophy
333	Hutchinson-Gilford syndrome

6

[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion

Pravastatin 💬

[10] 13, 46, 49, 67, 79, 96, 164, 210, 265, 333 💬

Disease ID	Name
13	Multiple sclerosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
67	Polycystic kidney disease
79	Homozygous familial hypercholesterolemia
96	Crohn disease
164	Oculocutaneous albinism
210	Single Ventricle
265	Lipodystrophy
333	Hutchinson-Gilford syndrome

7

[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion

Simvastatin 💬

[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis
15	Inclusion body myositis
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
66	IgA nephropathy
79	Homozygous familial hypercholesterolemia
86	Pulmonary arterial hypertension
89	Lymphangioleiomyomatosis
94	Primary sclerosing cholangitis
158	Tuberous sclerosis
160	Congenital ichthyosis
162	Pemphigoid
195	Noonan syndrome
265	Lipodystrophy
288	Autoimmune acquired coagulation factor deficiency
298	Hereditary pancreatitis
299	Cystic fibrosis
310	Congenital anomalies syndrome

8

[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion

Rosuvastatin calcium 💬

[13] 6, 18, 46, 49, 51, 56, 65, 79, 94, 96, 97, 271, 299 💬

Disease ID	Name
6	Parkinson disease
18	Spinocerebellar degeneration
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
56	Behcet disease
65	Primary immunodeficiency
79	Homozygous familial hypercholesterolemia
94	Primary sclerosing cholangitis
96	Crohn disease
97	Ulcerative colitis
271	Ankylosing spondylitis
299	Cystic fibrosis

9

[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion

Atorvastatin 💬

[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬

Disease ID	Name
13	Multiple sclerosis
22	Moyamoya disease
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
58	Hypertrophic cardiomyopathy
63	Idiopathic thrombocytopenic purpura
67	Polycystic kidney disease
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
88	Chronic thromboembolic pulmonary hypertension
93	Primary biliary cholangitis
96	Crohn disease
97	Ulcerative colitis
160	Congenital ichthyosis
225	Congenital nephrogenic diabetes insipidus
265	Lipodystrophy
271	Ankylosing spondylitis
297	Alagille syndrome
299	Cystic fibrosis

10

[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion

Lovastatin 💬

[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬

Disease ID	Name
6	Parkinson disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
79	Homozygous familial hypercholesterolemia
156	Rett syndrome
160	Congenital ichthyosis
195	Noonan syndrome
206	Fragile X syndrome
263	Cerebrotendinous xanthomatosis
280	Huge arteriovenous malformation with cervicofacial or limb lesion
310	Congenital anomalies syndrome

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