Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Neuroactive ligand-receptor interaction 💬

[2] ADORA1, ADORA2A 💬

[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
21	Mitochondrial disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
265	Lipodystrophy;

2

Neuroactive ligand-receptor interaction 💬

[2] ADORA1, ADORA2A 💬

Caffeine hydrate 💬

[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
21	Mitochondrial disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
265	Lipodystrophy;

3

Neuroactive ligand-receptor interaction 💬

[4] ADORA1, ADORA2A, ADORA2B, ADORA3 💬

[3] 13, 58, 65 💬

4

Neuroactive ligand-receptor interaction 💬

[4] ADORA1, ADORA2A, ADORA2B, ADORA3 💬

Adenosine phosphate 💬

Adenosine phosphate

[1] 46 💬

5

Neuroactive ligand-receptor interaction 💬

[2] ADORA1, ADORA2B 💬

Aminophylline 💬

[1] 63 💬

6

Neuroactive ligand-receptor interaction 💬

[2] ADORA1, ADORA2B 💬

Theophylline 💬

[2] 236, 299 💬

7

Neuroactive ligand-receptor interaction 💬

[2] ADORA1, ADORA2B 💬

Theophylline 💬

[2] 236, 299 💬

8

Neuroactive ligand-receptor interaction 💬

[1] ADORA2A 💬

Istradefylline 💬

[1] 6 💬

9

Neuroactive ligand-receptor interaction 💬

[1] ADORA2A 💬

Preladenant 💬

[1] 6 💬

10

Neuroactive ligand-receptor interaction 💬

[1] ADORA2A 💬

Regadenoson 💬

[1] 58 💬

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