Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[6] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alco ...

Secukinumab 💬

[8] 13, 37, 41, 46, 107, 160, 269, 271 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
37	Generalised pustular psoriasis
41	Giant cell arteritis
46	Malignant rheumatoid arthritis
107	Juvenile idiopathic arthritis
160	Congenital ichthyosis
269	Pyogenic arthritis
271	Ankylosing spondylitis

2

[6] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alco ...

Ixekizumab 💬

[8] 36, 37, 46, 107, 160, 162, 269, 271 💬

Disease ID	Name
36	Epidermolysis bullosa
37	Generalised pustular psoriasis
46	Malignant rheumatoid arthritis
107	Juvenile idiopathic arthritis
160	Congenital ichthyosis
162	Pemphigoid
269	Pyogenic arthritis
271	Ankylosing spondylitis

3

[6] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alco ...

Tibulizumab 💬

[1] 53 💬

4

[6] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Alco ...

Bimekizumab 💬

[3] 46, 97, 271 💬

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