Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | ABC transporters 💬 3 genes, 10 drugs (DrugBank) and 8 diseases |
ABCC8 [1] ABCC8 💬
|
Minoxidil Minoxidil 💬
| Minoxidil | 179 [1] 179 💬
|
2 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
3 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
4 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
5 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
6 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
7 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
8 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
9 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
10 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
HTR2A [1] HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
11 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
12 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
13 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
14 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
15 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
16 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
17 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
18 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
19 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
20 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
21 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
DRD2 [2] DRD2, HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
22 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
KCNJ11 [1] KCNJ11 💬
|
Minoxidil Minoxidil 💬
| Minoxidil | 179 [1] 179 💬
|
23 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
HTR2A [1] HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
24 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
ABCC8 [2] ABCC8, KCNJ11 💬
|
Minoxidil Minoxidil 💬
| Minoxidil | 179 [1] 179 💬
|
25 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
26 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
DRD2 [2] DRD2, HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
27 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
28 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
29 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
30 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 [1] SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
31 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
32 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
DRD2 [1] DRD2 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
33 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
34 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|
35 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
HTR2A [1] HTR2A 💬
|
Risperidone Risperidone 💬
| Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬
|
36 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 [1] SLC6A4 💬
|
Fluoxetine Fluoxetine 💬
| Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬
|
37 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 [2] SLC6A2, SLC6A3 💬
|
Methylphenidate Methylphenidate 💬
| Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬
|
38 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 [1] SLC6A4 💬
|
Fluoxetine Fluoxetine 💬
| Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬
|
39 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
ABCC8 [2] ABCC8, KCNJ11 💬
|
Minoxidil Minoxidil 💬
| Minoxidil | 179 [1] 179 💬
|
40 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
AGTR1 [1] AGTR1 💬
|
Losartan Losartan 💬
| Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
|