Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap jun ...

Risperidone 💬

[5] 8, 156, 179, 187, 206 💬

2

[16] Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...

[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬

Disease ID	Name
17	Multiple system atrophy
19	Lysosomal storage disease
36	Epidermolysis bullosa
58	Hypertrophic cardiomyopathy
66	IgA nephropathy
67	Polycystic kidney disease
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
98	Eosinophilic gastrointestinal disease
113	Muscular dystrophy
164	Oculocutaneous albinism
167	Marfan syndrome
179	Williams syndrome
215	Tetralogy of Fallot
222	Primary nephrotic syndrome
299	Cystic fibrosis

3

[5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic s ...

Risperidone 💬

[5] 8, 156, 179, 187, 206 💬

4

[3] Insulin secretion, GnRH secretion, Type II diabetes mellitus

[1] 179 💬

5

[1] Synaptic vesicle cycle

Methylphenidate 💬

Methylphenidate

[7] 6, 13, 34, 84, 113, 179, 206 💬

6

[7] Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - ...

Methylphenidate 💬

Methylphenidate

[7] 6, 13, 34, 84, 113, 179, 206 💬

7

[2] Synaptic vesicle cycle, Serotonergic synapse

Fluoxetine 💬

[6] 13, 17, 78, 86, 179, 206 💬

8

[3] ABC transporters, Insulin secretion, Type II diabetes mellitus

[1] 179 💬

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