Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
4 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
5 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
6 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
7 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
8 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
9 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
10 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
11 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
12 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
13 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
14 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
15 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
16 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
17 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
18 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
19 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
20 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
21 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
22 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
23 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
24 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
25 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
26 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
27 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
28 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
29 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
30 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
31 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
32 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
33 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
34 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
35 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
36 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
37 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
38 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
39 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
40 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
41 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
42 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
43 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
44 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
45 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
46 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
47 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
48 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
49 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
50 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
51 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
52 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
53 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
54 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
55 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
56 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
57 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
58 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR [1] HMGCR 💬
|
Rosuvastatin Rosuvastatin 💬
| Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
|
59 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
60 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
61 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
62 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
63 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
64 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
65 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
66 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
67 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
68 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
69 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
70 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
71 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
72 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
73 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
74 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
75 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
76 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
77 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
78 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
79 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
80 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
81 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
82 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
83 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
84 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
85 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
86 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
87 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
88 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
89 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
90 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
91 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
92 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
93 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
94 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
95 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
96 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
97 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR [1] HMGCR 💬
|
Rosuvastatin Rosuvastatin 💬
| Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
|
98 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
99 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
100 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
101 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
102 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
103 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
104 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
105 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
106 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
107 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
108 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
109 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
110 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
111 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
112 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
113 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
114 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
115 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
116 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
117 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
118 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
119 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
120 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
121 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
122 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
123 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
124 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
125 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
126 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
127 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
128 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
129 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
130 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
131 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
132 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
133 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
134 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
135 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
136 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
137 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
138 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
139 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
140 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
141 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
142 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
143 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
144 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
145 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
146 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
147 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
148 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
149 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
150 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
151 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
152 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
153 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
154 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
155 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
156 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
157 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
158 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
159 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
160 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
161 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
162 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA [3] PPP3CA, PPP3CB, PPP3CC 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
163 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
164 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
165 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
166 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
167 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
168 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
169 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
170 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
171 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
172 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
173 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
174 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
175 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
176 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
177 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
178 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
179 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
180 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
181 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
182 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
183 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
184 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
185 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
186 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 39 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
187 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
188 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
189 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
190 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
191 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
192 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
193 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
194 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
195 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
196 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
197 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
198 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
199 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
200 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
201 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
202 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
203 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
204 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
205 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
206 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 [1] MS4A1 💬
|
Rituximab Rituximab 💬
| Rituximab | 011 [48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
|
207 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
208 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
209 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
210 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
211 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
212 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IFNAR1 [1] IFNAR1 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
213 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IFNAR1 [1] IFNAR1 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
214 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
215 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
216 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
217 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
218 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
219 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
220 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
221 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
222 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
223 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
224 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
225 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
226 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
227 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
228 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
229 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
230 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
231 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
232 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
233 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
234 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
235 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
236 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
237 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
238 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
239 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
240 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
241 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
242 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
243 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
244 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
245 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
246 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
247 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
248 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
249 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
250 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
251 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
252 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
253 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
254 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
255 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
256 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
257 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
258 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
259 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
260 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
261 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
262 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
263 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
264 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL1R1 [2] IL1R1, IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
265 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
266 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
267 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
268 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
269 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
270 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
271 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
272 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
273 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
274 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
275 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
276 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
277 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
278 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
279 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
280 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
281 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
282 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
283 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
284 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
285 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
286 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
287 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
288 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
289 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
290 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
291 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
292 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
293 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
294 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
295 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
296 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
297 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
298 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
299 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
300 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
301 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
302 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
303 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
304 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
305 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
306 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
307 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
308 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
309 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
310 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
311 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
312 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
313 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
314 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
315 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
316 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
317 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
318 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
319 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
320 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
321 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
322 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
323 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
324 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
325 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
326 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
327 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
328 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
329 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
330 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
331 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
332 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
333 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
334 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
335 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
336 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
337 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
338 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
339 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
340 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
341 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
342 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
343 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
344 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
345 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
346 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
347 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
348 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
349 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
350 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
351 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
352 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
353 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL12A [1] IL12A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
354 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
355 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
356 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
357 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
358 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
359 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
360 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
361 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
362 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
363 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
364 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
365 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
366 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
367 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
368 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
369 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
370 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
371 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
372 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
373 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
374 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
375 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
376 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
377 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
378 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
379 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR [1] HMGCR 💬
|
Rosuvastatin Rosuvastatin 💬
| Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
|
380 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
381 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
382 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
383 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
384 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
385 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
386 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
387 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
388 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
389 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
390 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
391 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
392 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
393 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
394 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
395 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
396 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
397 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
398 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
399 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
400 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
401 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
402 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
403 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
404 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
405 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
406 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
407 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Prednisolone Prednisolone 💬
| Prednisolone | 003 [42] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
|
408 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬
|
Triamcinolone Triamcinolone 💬
| Triamcinolone | 035 [11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
|
409 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
410 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
411 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
412 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
413 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
414 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
415 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
416 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
417 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
418 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
419 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
420 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
421 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
422 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
423 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
424 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
425 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
426 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
427 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
428 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
429 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
430 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
431 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
432 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
433 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
434 | One carbon pool by folate 💬 3 genes, 2 drugs (DrugBank) and 38 diseases |
DHFR [2] DHFR, DHFR2 💬
|
Methotrexate Methotrexate 💬
| Methotrexate | 011 [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
|
435 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
436 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
437 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
438 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
439 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
440 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
441 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
442 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
443 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
444 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
445 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
446 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
447 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
448 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
449 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
450 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
451 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
452 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
453 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
454 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
455 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
456 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
457 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
458 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
459 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
460 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
461 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
462 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
463 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
464 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
465 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
466 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
467 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
468 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
469 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
470 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
471 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
472 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
473 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
474 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
475 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
476 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
477 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
478 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
479 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
480 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
481 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
482 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
483 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
484 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
485 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
486 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
487 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
488 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
489 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
490 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
491 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
492 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
493 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
494 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
495 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
496 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
497 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
498 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
499 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
500 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
501 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
502 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
503 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
504 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
505 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
506 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
507 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
508 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
509 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IL1R2 [1] IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
510 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IL12B [1] IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
511 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
512 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
513 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
514 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
515 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
516 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A [4] PDE4A, PDE4B, PDE4C, PDE4D 💬
|
Apremilast Apremilast 💬
| Apremilast | 046 [7] 46, 50, 56, 97, 107, 162, 271 💬
|
517 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
518 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
519 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
520 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
521 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
522 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL23A [1] IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
523 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
524 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
525 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
526 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
527 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
528 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
529 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
530 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
531 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
532 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
533 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
534 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
535 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
536 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
537 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
538 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
539 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
540 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
541 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬
|
Colchicine Colchicine 💬
| Colchicine | 002 [7] 2 , 42, 46, 56, 93, 210, 266 💬
|
542 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
543 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
544 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
545 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
546 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
547 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
548 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
549 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
550 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
551 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
552 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
553 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
554 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
555 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
556 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
557 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
558 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
559 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
560 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
561 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
562 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
563 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
564 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
565 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
566 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
567 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
568 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR [1] HMGCR 💬
|
Rosuvastatin Rosuvastatin 💬
| Rosuvastatin | 006 [11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
|
569 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
570 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
571 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
572 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
573 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
574 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
575 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
576 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
577 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
578 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
579 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
580 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
581 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1R1 [1] IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
582 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A [1] IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
583 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
584 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
585 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
586 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
587 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
588 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
589 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
590 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
591 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
592 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
593 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
594 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
595 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬
|
596 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IFNAR1 [2] IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 [1] 56 💬
|
597 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
598 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
599 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
600 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
601 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
602 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
603 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
604 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
605 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
606 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
607 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
608 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
609 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
610 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
611 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL1R2 [1] IL1R2 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 [18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
612 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL12A [3] IL12A, IL12B, IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
613 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
614 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
615 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
616 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
617 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
618 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
619 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
620 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
621 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
622 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
623 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR [1] VDR 💬
|
Cholecalciferol Cholecalciferol 💬
| Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
|
624 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL12A [2] IL12A, IL12B 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
625 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
626 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
627 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
628 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
629 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
630 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
631 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
632 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
633 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
634 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
635 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
636 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
637 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
638 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
639 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
640 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL2RA [1] IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
|
641 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R [1] IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
642 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
LTA [2] LTA, TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
643 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
644 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
645 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
646 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
647 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
648 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
649 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
650 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL1B [1] IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
651 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL1B [1] IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 [4] 41, 50, 56, 269 💬
|
652 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
653 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
654 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
|
655 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
656 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF [1] TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|