Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
2 Alcoholism 💬
 [2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
3 Alzheimer disease 💬
 [1] MAPT 💬 Flortaucipir F 18 💬 Flortaucipir [3]  5 ,  7 , 127 💬
4 Amphetamine addiction 💬
 [1] DRD1 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
5 Amphetamine addiction 💬
 [1] DRD1 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
6 Axon guidance 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
7 Calcium signaling pathway 💬
 [1] DRD1 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
8 Calcium signaling pathway 💬
 [2] DRD1, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
9 cAMP signaling pathway 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
10 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
11 cAMP signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
12 cGMP-PKG signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
13 Chemokine signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
14 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
15 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
16 Dopaminergic synapse 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
17 Dopaminergic synapse 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
18 Focal adhesion 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
19 Gap junction 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
20 Gap junction 💬
 [2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
21 Human cytomegalovirus infection 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
22 Insulin secretion 💬
 [1] SNAP25 💬 Botulinum toxin type A 💬 Botulinum toxin type A [14]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
23 Leukocyte transendothelial migration 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
24 Lipid and atherosclerosis 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
25 MAPK signaling pathway 💬
 [1] MAPT 💬 Flortaucipir F 18 💬 Flortaucipir [3]  5 ,  7 , 127 💬
26 MicroRNAs in cancer 💬
 [1] ROCK1 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
27 Morphine addiction 💬
 [1] DRD1 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
28 Morphine addiction 💬
 [1] DRD1 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
29 Neuroactive ligand-receptor interaction 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
30 Neuroactive ligand-receptor interaction 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
31 Oxytocin signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
32 Parkinson disease 💬
 [2] DRD1, DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
33 Parkinson disease 💬
 [2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
34 Parkinson disease 💬
 [1] MAPT 💬 Flortaucipir F 18 💬 Flortaucipir [3]  5 ,  7 , 127 💬
35 Pathogenic Escherichia coli infection 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
36 Pathways in cancer 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
37 Pathways of neurodegeneration - multiple diseases 💬
 [1] MAPT 💬 Flortaucipir F 18 💬 Flortaucipir [3]  5 ,  7 , 127 💬
38 Platelet activation 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
39 Proteoglycans in cancer 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
40 Rap1 signaling pathway 💬
 [1] DRD2 💬 Apomorphine 💬 Apomorphine [3]  5 ,  6 ,  7  💬
41 Rap1 signaling pathway 💬
 [1] DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
42 Regulation of actin cytoskeleton 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
43 Salmonella infection 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
44 Shigellosis 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
45 Sphingolipid signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
46 Synaptic vesicle cycle 💬
 [1] SNAP25 💬 Botulinum toxin type A 💬 Botulinum toxin type A [14]  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
47 TGF-beta signaling pathway 💬
 [1] ROCK1 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
48 Tight junction 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
49 Vascular smooth muscle contraction 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
50 Wnt signaling pathway 💬
 [1] ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
51 Yersinia infection 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬

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