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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

AGE-RAGE signaling pathway in diabetic complications 💬

[1] AGTR1 💬

Angiotensin II 💬

Angiotensin II

[7] 17, 19, 46, 66, 86, 222, 224 💬

Disease ID	Name
17	Multiple system atrophy;MSA-C;MSA-P;
19	Lysosomal storage disease;Lysosomal disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
86	Pulmonary arterial hypertension;PAH;
222	Primary nephrotic syndrome;
224	Purpura nephritis;

AGE-RAGE signaling pathway in diabetic complications 💬

[1] AGTR1 💬

Angiotensin II 💬

Angiotensin II

[7] 17, 19, 46, 66, 86, 222, 224 💬

Disease ID	Name
17	Multiple system atrophy;MSA-C;MSA-P;
19	Lysosomal storage disease;Lysosomal disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
86	Pulmonary arterial hypertension;PAH;
222	Primary nephrotic syndrome;
224	Purpura nephritis;

AGE-RAGE signaling pathway in diabetic complications 💬

[1] AGTR1 💬

Candesartan 💬

Candesartan

[2] 58, 67 💬

AGE-RAGE signaling pathway in diabetic complications 💬

[1] AGTR1 💬

Candesartan cilexetil 💬

Candesartan cilexetil

[1] 67 💬

AGE-RAGE signaling pathway in diabetic complications 💬

[1] AGTR1 💬

Irbesartan 💬

Irbesartan

[4] 66, 167, 168, 222 💬

AGE-RAGE signaling pathway in diabetic complications 💬

[1] AGTR1 💬

Losartan 💬

Losartan

[17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬

Disease ID	Name
17	Multiple system atrophy;MSA-C;MSA-P;
19	Lysosomal storage disease;Lysosomal disease;
36	Epidermolysis bullosa;
58	Hypertrophic cardiomyopathy;HCM;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
67	Polycystic kidney disease;PKD;PCKD;Polycystic kidney;
85	Idiopathic interstitial pneumonia;IIPs;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
113	Muscular dystrophy;
164	Oculocutaneous albinism;
167	Marfan syndrome;
179	Williams syndrome;
215	Tetralogy of Fallot;Fallot tetralogy;
222	Primary nephrotic syndrome;
299	Cystic fibrosis;

AGE-RAGE signaling pathway in diabetic complications 💬

[1] AGTR1 💬

Sparsentan 💬

Sparsentan

[3] 66, 218, 222 💬

AGE-RAGE signaling pathway in diabetic complications 💬

[1] AGTR1 💬

Telmisartan 💬

Telmisartan

[2] 66, 67 💬

AGE-RAGE signaling pathway in diabetic complications 💬

[1] AGTR1 💬

Valsartan 💬

Valsartan

[7] 57, 58, 66, 75, 218, 222, 224 💬

Disease ID	Name
57	Idiopathic dilated cardiomyopathy;
58	Hypertrophic cardiomyopathy;HCM;
66	IgA nephropathy;IgA nephritis;Berger disease;IgA-IgG nephropathy;
75	Cushing disease;Cushing;
218	Alport syndrome;
222	Primary nephrotic syndrome;
224	Purpura nephritis;

AGE-RAGE signaling pathway in diabetic complications 💬

[1] BCL2 💬

Venetoclax 💬

Venetoclax

[1] 28 💬

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