Target Gene/Pathway Pathway / Gene

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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Central carbon metabolism in cancer 💬

[1] EGFR 💬

[2] 51, 86 💬

2

Central carbon metabolism in cancer 💬

[1] EGFR 💬

[1] 94 💬

3

Central carbon metabolism in cancer 💬

[1] EGFR 💬

[1] 75 💬

4

Central carbon metabolism in cancer 💬

[1] EGFR 💬

[1] 34 💬

5

Central carbon metabolism in cancer 💬

[2] EGFR, ERBB2 💬

[3] 34, 74, 75 💬

6

Central carbon metabolism in cancer 💬

[2] EGFR, ERBB2 💬

[1] 34 💬

7

Central carbon metabolism in cancer 💬

[2] EGFR, ERBB2 💬

Tesevatinib 💬

[1] 67 💬

8

Central carbon metabolism in cancer 💬

[3] FGFR1, FGFR2, FGFR3 💬

Infigratinib 💬

[1] 276 💬

9

Central carbon metabolism in cancer 💬

[5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬

Name	Full Name
FGFR1	fibroblast growth factor receptor 1
FGFR2	fibroblast growth factor receptor 2
FGFR3	fibroblast growth factor receptor 3
PDGFRA	platelet derived growth factor receptor alpha
PDGFRB	platelet derived growth factor receptor beta

Nintedanib 💬

[5] 51, 85, 89, 227, 228 💬

Disease ID	Name
51	Scleroderma;Systemic sclerosis;SSc;
85	Idiopathic interstitial pneumonia;IIPs;
89	Lymphangioleiomyomatosis;LAM;
227	Osler disease;Hereditary hemorrhagic telangiectasia;Osler-Weber-Rendu disease;
228	Bronchiolitis obliterans;Obliterating bronchiolitis;

10

Central carbon metabolism in cancer 💬

[1] FGFR2 💬

Palifermin 💬

[5] 13, 36, 38, 39, 65 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
36	Epidermolysis bullosa;
38	Stevens-Johnson syndrome;SJS;Mucocutaneous ocular syndrome;
39	Toxic epidermal necrolysis;Toxic epidermal necrosis;TEN;
65	Primary immunodeficiency;

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