Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Fc epsilon RI signaling pathway 💬
 [1] ALOX5 💬 Oxatomide 💬 Oxatomide [1] 113 💬 💬
2 Fc epsilon RI signaling pathway 💬
 [1] ALOX5 💬 Zileuton 💬 Zileuton [3] 85, 160, 164 💬 💬
3 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Acalabrutinib 💬 Acalabrutinib [2] 46, 61 💬 💬
4 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Branebrutinib 💬 Branebrutinib [3] 46, 49, 53 💬 💬
5 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Evobrutinib 💬 Evobrutinib [3] 13, 46, 49 💬 💬
6 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Fenebrutinib 💬 Fenebrutinib [1] 13 💬 💬
7 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Ibrutinib 💬 Ibrutinib [3] 28, 60, 61 💬 💬
8 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Orelabrutinib 💬 Orelabrutinib [4] 13, 49, 61, 63 💬 💬
9 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Remibrutinib 💬 Remibrutinib [2] 13, 53 💬 💬
10 Fc epsilon RI signaling pathway 💬
 [1] BTK 💬 Zanubrutinib 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬 💬
11 Fc epsilon RI signaling pathway 💬
 [1] CSF2 💬 Otilimab 💬 Otilimab [1] 46 💬 💬
12 Fc epsilon RI signaling pathway 💬
 [1] FCER1A 💬 Omalizumab 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬 💬
13 Fc epsilon RI signaling pathway 💬
 [1] FYN 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
14 Fc epsilon RI signaling pathway 💬
 [1] FYN 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
15 Fc epsilon RI signaling pathway 💬
 [1] IL13 💬 Anrukinzumab 💬 Anrukinzumab [1] 97 💬 💬
16 Fc epsilon RI signaling pathway 💬
 [1] IL13 💬 Lebrikizumab 💬 Lebrikizumab [1] 85 💬 💬
17 Fc epsilon RI signaling pathway 💬
 [1] IL13 💬 Tralokinumab 💬 Tralokinumab [2] 85, 97 💬 💬
18 Fc epsilon RI signaling pathway 💬
 [1] IL4 💬 Binetrakin 💬 Binetrakin [1] 46 💬 💬
19 Fc epsilon RI signaling pathway 💬
 [1] IL5 💬 Mepolizumab 💬 Mepolizumab [4] 44, 45, 98, 162 💬 💬
20 Fc epsilon RI signaling pathway 💬
 [1] IL5 💬 Reslizumab 💬 Reslizumab [2] 44, 98 💬 💬
21 Fc epsilon RI signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
22 Fc epsilon RI signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
23 Fc epsilon RI signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
24 Fc epsilon RI signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
25 Fc epsilon RI signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
26 Fc epsilon RI signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
27 Fc epsilon RI signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
28 Fc epsilon RI signaling pathway 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
29 Fc epsilon RI signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
30 Fc epsilon RI signaling pathway 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
31 Fc epsilon RI signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
32 Fc epsilon RI signaling pathway 💬
 [1] SYK 💬 Fostamatinib 💬 Fostamatinib [4] 46, 49, 61, 66 💬 💬
33 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
34 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
35 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
36 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
37 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
38 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
39 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬 💬
40 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬 💬
41 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
42 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬 💬
43 Fc epsilon RI signaling pathway 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬