Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 76 entries
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 [6] FLT1, FLT4, KDR, PDGFRA, PDGFRB, RET 💬
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Sunitinib Sunitinib 💬Calcium signaling pathway
| Sunitinib | 028 [2] 28, 34 💬
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| 2 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT4 [4] FLT4, KDR, PDGFRB, RET 💬
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Sorafenib Sorafenib 💬Calcium signaling pathway
| Sorafenib | 034 [2] 34, 86 💬
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| 3 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FLT3 [5] FLT3, KIT, PDGFRA, PDGFRB, RET 💬
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Sunitinib Sunitinib 💬Central carbon metabolism in cancer
| Sunitinib | 028 [2] 28, 34 💬
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| 4 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FLT3 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬
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Sorafenib Sorafenib 💬Central carbon metabolism in cancer
| Sorafenib | 034 [2] 34, 86 💬
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| 5 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
BRAF [3] BRAF, RAF1, RET 💬
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Sorafenib Sorafenib 💬Non-small cell lung cancer
| Sorafenib | 034 [2] 34, 86 💬
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| 6 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RET [1] RET 💬Non-small cell lung cancer
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Sunitinib Sunitinib 💬Non-small cell lung cancer
| Sunitinib | 028 [2] 28, 34 💬
|
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| 7 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
BRAF [7] BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬Pathways in cancer
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Sorafenib Sorafenib 💬Pathways in cancer
| Sorafenib | 034 [2] 34, 86 💬
|
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| 8 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF1R [7] CSF1R, FLT3, FLT4, KIT, PDGFRA, PDGFRB, RET 💬Pathways in cancer
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Sunitinib Sunitinib 💬Pathways in cancer
| Sunitinib | 028 [2] 28, 34 💬
|
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| 9 | Protein processing in endoplasmic reticulum 💬 3 genes, 3 drugs (DrugBank) and 3 diseases |
BCL2 [1] BCL2 💬Protein processing in endoplasmic reticulum
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Venetoclax Venetoclax 💬Protein processing in endoplasmic reticulum
| Venetoclax | 028 [1] 28 💬9. Protein processing in endoplasmic reticulum
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| 10 | Protein processing in endoplasmic reticulum 💬 3 genes, 3 drugs (DrugBank) and 3 diseases |
MAP3K5 [1] MAP3K5 💬Protein processing in endoplasmic reticulum
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Selonsertib Selonsertib 💬Protein processing in endoplasmic reticulum
| Selonsertib | 086 [1] 86 💬10. Protein processing in endoplasmic reticulum
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