Target Gene/Pathway Pathway / Gene

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No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Sphingolipid signaling pathway 💬

[1] ADORA1 💬

Aminophylline 💬

[1] 63 💬

2

Sphingolipid signaling pathway 💬

[1] ADORA1 💬

[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
21	Mitochondrial disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
265	Lipodystrophy;

3

Sphingolipid signaling pathway 💬

[1] ADORA1 💬

Caffeine hydrate 💬

[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
6	Parkinson disease;Disease Parkinson's;
21	Mitochondrial disease;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
78	Hypopituitarism;Anterior pituitary hypothyroidism;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
265	Lipodystrophy;

4

Sphingolipid signaling pathway 💬

[1] ADORA1 💬

Theophylline 💬

[2] 236, 299 💬

5

Sphingolipid signaling pathway 💬

[1] ADORA1 💬

Theophylline 💬

[2] 236, 299 💬

6

Sphingolipid signaling pathway 💬

[2] ADORA1, ADORA3 💬

[3] 13, 58, 65 💬

7

Sphingolipid signaling pathway 💬

[2] ADORA1, ADORA3 💬

Adenosine phosphate 💬

Adenosine phosphate

[1] 46 💬

8

Sphingolipid signaling pathway 💬

[1] ADORA3 💬

Piclidenoson 💬

[1] 46 💬

9

Sphingolipid signaling pathway 💬

[1] BCL2 💬

Venetoclax 💬

[1] 28 💬

10

Sphingolipid signaling pathway 💬

[1] FCER1A 💬

Omalizumab 💬

[7] 46, 53, 65, 98, 162, 226, 299 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
65	Primary immunodeficiency;
98	Eosinophilic gastrointestinal disease;Eosinophilic gastroenteritis;Eosinophilic esophagitis;Eosinophilic colitis;Eosinophilic gastro-intestinal disorder;EGID;
162	Pemphigoid;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
299	Cystic fibrosis;

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