Gene

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No.	KEGG PATHWAY	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Necroptosis 💬	[1] BCL2 💬	Venetoclax 💬	Venetoclax	[1] 28 💬 💬
2	Necroptosis 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬	Rontalizumab 💬	Rontalizumab	[1] 49 💬 💬
3	Necroptosis 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬	Sifalimumab 💬	Sifalimumab	[1] 49 💬 💬
4	Necroptosis 💬	[2] IFNAR1, IFNAR2 💬	Anifrolumab 💬	Anifrolumab	[3] 46, 49, 53 💬 💬
5	Necroptosis 💬	[2] IFNAR1, IFNAR2 💬	Interferon alfa 💬	Interferon alfa	[6] 13, 25, 26, 28, 56, 96 💬 💬
6	Necroptosis 💬	[2] IFNAR1, IFNAR2 💬	Interferon alfa-2a 💬	Interferon alfa-2a	[1] 56 💬 💬
7	Necroptosis 💬	[2] IFNAR1, IFNAR2 💬	Interferon alfa-2b 💬	Interferon alfa-2b	[2] 25, 34 💬 💬
8	Necroptosis 💬	[2] IFNAR1, IFNAR2 💬	Interferon beta-1a 💬	Interferon beta-1a	[4] 13, 26, 96, 97 💬 💬
9	Necroptosis 💬	[2] IFNAR1, IFNAR2 💬	Interferon beta-1b 💬	Interferon beta-1b	[1] 13 💬 💬
10	Necroptosis 💬	[2] IFNAR1, IFNAR2 💬	Peginterferon beta-1a 💬	Peginterferon beta-1a	[1] 13 💬 💬
11	Necroptosis 💬	[1] IFNG 💬	Emapalumab 💬	Emapalumab	[3] 49, 65, 107 💬 💬
12	Necroptosis 💬	[1] IFNG 💬	Fontolizumab 💬	Fontolizumab	[1] 46 💬 💬
13	Necroptosis 💬	[2] IFNGR1, IFNGR2 💬	Interferon gamma-1b 💬	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬 💬
14	Necroptosis 💬	[1] IL1A 💬	Bermekimab 💬	Bermekimab	[1] 51 💬 💬
15	Necroptosis 💬	[2] IL1A, IL1B 💬	Rilonacept 💬	Rilonacept	[4] 51, 106, 107, 266 💬 💬
16	Necroptosis 💬	[3] IL1A, IL1B, TNF 💬	Pirfenidone 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
17	Necroptosis 💬	[1] IL1B 💬	Canakinumab 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
18	Necroptosis 💬	[1] IL1B 💬	Gevokizumab 💬	Gevokizumab	[4] 41, 50, 56, 269 💬 💬
19	Necroptosis 💬	[1] JAK1 💬	Abrocitinib 💬	Abrocitinib	[1] 84 💬 💬
20	Necroptosis 💬	[1] JAK1 💬	Filgotinib 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬 💬
21	Necroptosis 💬	[1] JAK1 💬	Itacitinib 💬	Itacitinib	[4] 46, 51, 97, 228 💬 💬
22	Necroptosis 💬	[1] JAK1 💬	Upadacitinib 💬	Upadacitinib	[8] 40, 41, 46, 49, 96, 97, 107, 271 💬 💬
23	Necroptosis 💬	[2] JAK1, JAK2 💬	Baricitinib 💬	Baricitinib	[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬
24	Necroptosis 💬	[2] JAK1, JAK2 💬	Ruxolitinib 💬	Ruxolitinib	[3] 60, 65, 228 💬 💬
25	Necroptosis 💬	[3] JAK1, JAK2, JAK3 💬	Peficitinib 💬	Peficitinib	[1] 46 💬 💬
26	Necroptosis 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	Tofacitinib 💬	Tofacitinib	[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
27	Necroptosis 💬	[1] PARP1 💬	Olaparib 💬	Olaparib	[2] 86, 285 💬 💬
28	Necroptosis 💬	[1] SMPD1 💬	Olipudase alfa 💬	Olipudase alfa	[1] 19 💬 💬
29	Necroptosis 💬	[1] TNF 💬	Adalimumab 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
30	Necroptosis 💬	[1] TNF 💬	Certolizumab pegol 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
31	Necroptosis 💬	[1] TNF 💬	Etanercept 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
32	Necroptosis 💬	[1] TNF 💬	Golimumab 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
33	Necroptosis 💬	[1] TNF 💬	Infliximab 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
34	Necroptosis 💬	[1] TNF 💬	Lenalidomide 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
35	Necroptosis 💬	[1] TNF 💬	Ozoralizumab 💬	Ozoralizumab	[1] 46 💬 💬
36	Necroptosis 💬	[1] TNF 💬	Pegsunercept 💬	Pegsunercept	[1] 46 💬 💬
37	Necroptosis 💬	[1] TNF 💬	Pomalidomide 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬 💬
38	Necroptosis 💬	[1] TNF 💬	Thalidomide 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬
39	Necroptosis 💬	[1] TYK2 💬	Deucravacitinib 💬	Deucravacitinib	[3] 49, 96, 97 💬 💬